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Found 25 results
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Year
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2023
Metzler VM
,
de Brot S
,
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Nilsson EM
,
Ntekim A
,
Persson JL
,
Robinson BD
et al.
. 2023.
The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.
.
Front Cell Dev Biol. 11:1116424.
Kubala JM
,
Laursen KB
,
Schreiner R
,
Williams RM
,
van der Mijn JC
,
Crowley MJ
,
Mongan NP
,
Nanus DM
,
Heller DA
,
Gudas LJ
. 2023.
NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.
.
Cancer Biol Ther. 24(1):2170669.
2022
Lothion-Roy J
,
Haigh DB
,
Harris AE
,
Metzler VM
,
Alsaleem M
,
Toss MS
,
Kariri Y
,
Ntekim A
,
Robinson BD
,
Khani F
et al.
. 2022.
Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.
.
Front Genet. 13:1096071.
Harris AE
,
Metzler VM
,
Lothion-Roy J
,
Varun D
,
Woodcock CL
,
Haigh DB
,
Endeley C
,
Haque M
,
Toss MS
,
Alsaleem M
et al.
. 2022.
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.
.
Front Endocrinol (Lausanne). 13:1006101.
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Metzler VM
,
Persson JL
,
Robinson BD
,
Khani F
,
Alsaleem M
,
Ntekim A
et al.
. 2022.
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
.
Cancers (Basel). 14(20)
van der Mijn JC
,
Chen Q
,
Laursen KB
,
Khani F
,
Wang X
,
Dorsaint P
,
Sboner A
,
Gross SS
,
Nanus DM
,
Gudas LJ
. 2022.
Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR).
.
Mol Carcinog.
2021
Williams RM
,
Shah J
,
Mercer E
,
Tian HS
,
Thompson V
,
Cheung JM
,
Dorso M
,
Kubala JM
,
Gudas LJ
,
de Stanchina E
et al.
. 2021.
Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury.
.
Front Pharmacol. 12:790913.
Tang X-H
,
Gambardella J
,
Jankauskas S
,
Wang X
,
Santulli G
,
Gudas LJ
,
Levi R
. 2021.
A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.
.
J Pharmacol Exp Ther. 379(2):182-190.
2020
Molina AM
,
van der Mijn JC
,
Christos P
,
Wright J
,
Thomas C
,
Dutcher JP
,
Nanus DM
,
Tagawa ST
,
Gudas LJ
. 2020.
NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.
.
Invest New Drugs.
2019
Orfali N
,
Jeyapalan JN
,
Woodcock CL
,
O'Donovan TR
,
Benjamin D
,
Cahill M
,
McKenna S
,
Gudas LJ
,
Mongan NP
. 2019.
Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.
.
Methods Mol Biol. 2019:33-49.
2016
Simandi Z
,
Horvath A
,
Wright LC
,
Cuaranta-Monroy I
,
De Luca I
,
Karolyi K
,
Sauer S
,
Deleuze J-F
,
Gudas LJ
,
Cowley SM
et al.
. 2016.
OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation.
.
Mol Cell. 63(4):647-661.
2015
Williams RM
,
Shah J
,
Ng BD
,
Minton DR
,
Gudas LJ
,
Park CY
,
Heller DA
. 2015.
Mesoscale nanoparticles selectively target the renal proximal tubule epithelium.
.
Nano Lett. 15(4):2358-64.
Nilsson EM
,
Laursen KB
,
Whitchurch J
,
McWilliam A
,
Ødum N
,
Persson JL
,
Heery DM
,
Gudas LJ
,
Mongan NP
. 2015.
MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.
.
Oncotarget. 6(34):35710-25.
2013
Fu L
,
Wang G
,
Shevchuk MM
,
Nanus DM
,
Gudas LJ
. 2013.
Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.
.
Cancer Res. 73(9):2916-25.
Benoit YD
,
Laursen KB
,
Witherspoon MS
,
Lipkin SM
,
Gudas LJ
. 2013.
Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
.
J Cell Physiol. 228(4):764-72.
Benoit YD
,
Witherspoon MS
,
Laursen KB
,
Guezguez A
,
Beauséjour M
,
Beaulieu J-F
,
Lipkin SM
,
Gudas LJ
. 2013.
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
.
Exp Cell Res. 319(10):1463-70.
2012
Laursen KB
,
Wong P-M
,
Gudas LJ
. 2012.
Epigenetic regulation by RARα maintains ligand-independent transcriptional activity.
.
Nucleic Acids Res. 40(1):102-15.
2011
Fu L
,
Wang G
,
Shevchuk MM
,
Nanus DM
,
Gudas LJ
. 2011.
Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.
.
Cancer Res. 71(21):6848-56.
Gudas LJ
,
Wagner JA
. 2011.
Retinoids regulate stem cell differentiation.
.
J Cell Physiol. 226(2):322-30.
2010
Wang G
,
Badylak SF
,
Heber-Katz E
,
Braunhut SJ
,
Gudas LJ
. 2010.
The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.
.
Regen Med. 5(2):201-20.
Agrawal V
,
Johnson SA
,
Reing J
,
Zhang L
,
Tottey S
,
Wang G
,
Hirschi KK
,
Braunhut S
,
Gudas LJ
,
Badylak SF
. 2010.
Epimorphic regeneration approach to tissue replacement in adult mammals.
.
Proc Natl Acad Sci U S A. 107(8):3351-5.
Wang R
,
Wang G
,
Ricard MJ
,
Ferris B
,
Strulovici-Barel Y
,
Salit J
,
Hackett NR
,
Gudas LJ
,
Crystal RG
. 2010.
Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.
.
Chest. 138(6):1402-10.
Wang R
,
Wang G
,
Ricard MJ
,
Ferris B
,
Strulovici-Barel Y
,
Salit J
,
Hackett NR
,
Gudas LJ
,
Crystal RG
. 2010.
Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.
.
Chest. 138(6):1402-10.
2008
Lane MA
,
Xu J
,
Wilen EW
,
Sylvester R
,
Derguini F
,
Gudas LJ
. 2008.
LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol.
.
Mol Cell Endocrinol. 280(1-2):63-74.
2003
Mohn D
,
Chen SW
,
Dias DCampos
,
Weinstein DC
,
Dyer MA
,
Sahr K
,
Ducker CE
,
Zahradka E
,
Keller G
,
Zaret KS
et al.
. 2003.
Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos.
.
Dev Dyn. 226(3):446-59.