Publications

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2013.  Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.. Cancer Res. 73(9):2916-25.

Orfali N, O'Donovan TR, Cahill MR, Benjamin D, Nanus DM, McKenna SL, Gudas LJ, Mongan NP.  2020.  All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).. Eur J Haematol. 104(3):236-250.

Benjamin DN, O'Donovan TR, Laursen KB, Orfali N, Cahill MR, Mongan NP, Gudas LJ, McKenna SL.  2022.  All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.. Front Oncol. 12:848517.

Marcinkiewicz KM, Gudas LJ.  2014.  Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells.. Exp Cell Res. 320(1):128-43.

Marcinkiewicz KM, Gudas LJ.  2014.  Altered histone mark deposition and DNA methylation at homeobox genes in human oral squamous cell carcinoma.. J Cell Physiol. 229(10):1405-16.

Laursen KB, Kashyap V, Scandura J, Gudas LJ.  2015.  An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency.. J Biol Chem. 290(7):4356-66.

Trasino SE, Tang X-H, Shevchuk MM, Choi ME, Gudas LJ.  2018.  Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor 2 Agonist.. J Pharmacol Exp Ther. 367(1):82-94.

Minton DR, Fu L, Chen Q, Robinson BD, Gross SS, Nanus DM, Gudas LJ.  2015.  Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma.. PLoS One. 10(4):e0120649.

Scotland KB, Chen S, Sylvester R, Gudas LJ.  2009.  Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation.. Dev Dyn. 238(8):1863-77.

Huang D, Chen SW, Gudas LJ.  2002.  Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice.. Dev Dyn. 223(3):353-70.

Marcinkiewicz K, Scotland KB, Boorjian SA, Nilsson EM, Persson JLiao, Abrahamsson PAnders, Allegrucci C, Hughes IA, Gudas LJ, Mongan NP.  2012.  The androgen receptor and stem cell pathways in prostate and bladder cancers (review).. Int J Oncol. 40(1):5-12.

Boorjian S, Ugras S, Mongan NP, Gudas LJ, You X, Tickoo SK, Scherr DS.  2004.  Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.. Urology. 64(2):383-8.

Chi Y, Del Aguila EMere, Zhang T, Warren CD, Hoxie HR, Chen Q, Gross SS, Geri JB, Nanus DM, Gudas LJ.  2025.  ATF4 in proximal tubules modulates kidney function and modifies the metabolome.. J Mol Med (Berl).

Tang X-H, Scognamiglio T, Gudas LJ.  2013.  Basal stem cells contribute to squamous cell carcinomas in the oral cavity.. Carcinogenesis. 34(5):1158-64.

Quintero CM, Laursen KB, Mongan NP, Luo M, Gudas LJ.  2018.  CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.. J Mol Biol. 430(21):4168-4182.

Hedblom A, Laursen KB, Miftakhova R, Sarwar M, Anagnostaki L, Bredberg A, Mongan NP, Gudas LJ, Persson JL.  2013.  CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.. Cell Cycle. 12(8):1251-66.

Tang X-H, Suh M-J, Li R, Gudas LJ.  2007.  Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.. J Lipid Res. 48(1):165-76.

Brennan EP, Tang X-H, Stewart-Akers AM, Gudas LJ, Badylak SF.  2008.  Chemoattractant activity of degradation products of fetal and adult skin extracellular matrix for keratinocyte progenitor cells.. J Tissue Eng Regen Med. 2(8):491-8.

Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F et al..  2022.  Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.. Front Genet. 13:1096071.

Tang X-H, Osei-Sarfo K, Urvalek AM, Zhang T, Scognamiglio T, Gudas LJ.  2014.  Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Proc Natl Acad Sci U S A. 111(24):8907-12.

Laursen KB, Gudas LJ.  2018.  Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.. J Biol Chem. 293(30):11891-11900.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.

Laursen KB, Gudas LJ.  2014.  Crossing the barrier: STRA6 in epidermal differentiation.. J Invest Dermatol. 134(6):1504-1506.

Langton S, Gudas LJ.  2008.  CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid.. Dev Biol. 315(2):331-54.

Ricard MJ, Gudas LJ.  2013.  Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells.. J Biol Chem. 288(40):28801-13.