Publications

Fernandez CC, Gudas LJ.  2009.  The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells.. J Cell Biochem. 106(3):427-43.

Wang G, Badylak SF, Heber-Katz E, Braunhut SJ, Gudas LJ.  2010.  The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.. Regen Med. 5(2):201-20.

Kashyap V, Gudas LJ.  2010.  Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts.. J Biol Chem. 285(19):14534-48.

Agrawal V, Johnson SA, Reing J, Zhang L, Tottey S, Wang G, Hirschi KK, Braunhut S, Gudas LJ, Badylak SF.  2010.  Epimorphic regeneration approach to tissue replacement in adult mammals.. Proc Natl Acad Sci U S A. 107(8):3351-5.

Liu L, Tang X-H, Scognamiglio T, Gudas LJ.  2010.  Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice.. J Nutr Biochem. 21(10):975-82.

David KA, Mongan NP, Smith C, Gudas LJ, Nanus DM.  2010.  Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.. Cancer Biol Ther. 9(9):678-84.

Wang R, Wang G, Ricard MJ, Ferris B, Strulovici-Barel Y, Salit J, Hackett NR, Gudas LJ, Crystal RG.  2010.  Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.. Chest. 138(6):1402-10.

Lee M-Y, Lu A, Gudas LJ.  2010.  Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells.. J Cell Physiol. 224(1):17-27.

Kashyap V, Gudas LJ, Brenet F, Funk P, Viale A, Scandura JM.  2011.  Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid.. J Biol Chem. 286(5):3250-60.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2011.  Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.. Cancer Res. 71(21):6848-56.

Reynertson KA, Charlson ME, Gudas LJ.  2011.  Induction of murine embryonic stem cell differentiation by medicinal plant extracts.. Exp Cell Res. 317(1):82-93.

Amat R, Gudas LJ.  2011.  RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells.. J Cell Physiol. 226(2):293-8.

Gudas LJ, Wagner JA.  2011.  Retinoids regulate stem cell differentiation.. J Cell Physiol. 226(2):322-30.

Tang X-H, Gudas LJ.  2011.  Retinoids, retinoic acid receptors, and cancer.. Annu Rev Pathol. 6:345-64.

Rezende NC, Lee M-Y, Monette S, Mark W, Lu A, Gudas LJ.  2011.  Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression.. Dev Biol. 356(2):370-82.

Marcinkiewicz K, Scotland KB, Boorjian SA, Nilsson EM, Persson JLiao, Abrahamsson PAnders, Allegrucci C, Hughes IA, Gudas LJ, Mongan NP.  2012.  The androgen receptor and stem cell pathways in prostate and bladder cancers (review).. Int J Oncol. 40(1):5-12.

Gudas LJ.  2012.  Emerging roles for retinoids in regeneration and differentiation in normal and disease states.. Biochim Biophys Acta. 1821(1):213-21.

Laursen KB, Wong P-M, Gudas LJ.  2012.  Epigenetic regulation by RARα maintains ligand-independent transcriptional activity.. Nucleic Acids Res. 40(1):102-15.

Benoit YD, Lepage MB, Khalfaoui T, Tremblay E, Basora N, Carrier JC, Gudas LJ, Beaulieu J-F.  2012.  Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.. J Cell Sci. 125(Pt 14):3454-63.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2013.  Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.. Cancer Res. 73(9):2916-25.

Tang X-H, Scognamiglio T, Gudas LJ.  2013.  Basal stem cells contribute to squamous cell carcinomas in the oral cavity.. Carcinogenesis. 34(5):1158-64.

Hedblom A, Laursen KB, Miftakhova R, Sarwar M, Anagnostaki L, Bredberg A, Mongan NP, Gudas LJ, Persson JL.  2013.  CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.. Cell Cycle. 12(8):1251-66.

Ricard MJ, Gudas LJ.  2013.  Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells.. J Biol Chem. 288(40):28801-13.

Pérez RJ, Benoit YD, Gudas LJ.  2013.  Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.. Exp Cell Res. 319(14):2196-204.

Kauffman EC, Robinson BD, Downes M, Marcinkiewicz K, Vourganti S, Scherr DS, Gudas LJ, Mongan NP.  2013.  Estrogen receptor-β expression and pharmacological targeting in bladder cancer.. Oncol Rep. 30(1):131-8.