Publications

Goldberg JS, Vargas M, Rosmarin AS, Milowsky MI, Papanicoloau N, Gudas LJ, Shelton G, Feit K, Petrylak D, Nanus DM.  2002.  Phase I trial of interferon alpha2b and liposome-encapsulated all-trans retinoic acid in the treatment of patients with advanced renal cell carcinoma.. Cancer. 95(6):1220-7.

Cerignoli F, Guo X, Cardinali B, Rinaldi C, Casaletto J, Frati L, Screpanti I, Gudas LJ, Gulino A, Thiele CJ et al..  2002.  retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines.. Cancer Res. 62(4):1196-204.

Zhuang Y, Faria TN, Chambon P, Gudas LJ.  2003.  Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells.. Mol Cancer Res. 1(8):619-30.

Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR.  2003.  Retinoic acid receptor-mediated induction of ABCA1 in macrophages.. Mol Cell Biol. 23(21):7756-66.

Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ.  2004.  Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells.. Exp Cell Res. 294(1):290-300.

Fernandez CC, Gudas LJ.  2009.  The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells.. J Cell Biochem. 106(3):427-43.

Wang R, Wang G, Ricard MJ, Ferris B, Strulovici-Barel Y, Salit J, Hackett NR, Gudas LJ, Crystal RG.  2010.  Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.. Chest. 138(6):1402-10.

Kashyap V, Gudas LJ, Brenet F, Funk P, Viale A, Scandura JM.  2011.  Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid.. J Biol Chem. 286(5):3250-60.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2011.  Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.. Cancer Res. 71(21):6848-56.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2013.  Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.. Cancer Res. 73(9):2916-25.

Gudas LJ, Fu L, Minton DR, Mongan NP, Nanus DM.  2014.  The role of HIF1α in renal cell carcinoma tumorigenesis.. J Mol Med (Berl). 92(8):825-36.

Minton DR, Fu L, Chen Q, Robinson BD, Gross SS, Nanus DM, Gudas LJ.  2015.  Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma.. PLoS One. 10(4):e0120649.

Fu L, Minton DR, Zhang T, Nanus DM, Gudas LJ.  2015.  Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome.. Mol Cancer Res. 13(5):870-8.

Minton DR, Fu L, Mongan NP, Shevchuk MM, Nanus DM, Gudas LJ.  2016.  Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma.. Clin Cancer Res. 22(11):2791-801.

Sureshbabu A, Patino E, Ma KC, Laursen K, Finkelsztein EJ, Akchurin O, Muthukumar T, Ryter SW, Gudas L, Choi AMK et al..  2018.  RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction.. JCI Insight. 3(11)

van der Mijn JC, Awamlh BAl Hussein, Khan AIslam, Posada-Calderon L, Oromendia C, Fainberg J, Alshak M, Elahjji R, Pierce H, Taylor B et al..  2019.  Validation of risk factors for recurrence of renal cell carcinoma: Results from a large single-institution series.. PLoS One. 14(12):e0226285.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.

Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F et al..  2022.  Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.. Front Genet. 13:1096071.

Harris AE, Metzler VM, Lothion-Roy J, Varun D, Woodcock CL, Haigh DB, Endeley C, Haque M, Toss MS, Alsaleem M et al..  2022.  Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.. Front Endocrinol (Lausanne). 13:1006101.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol.

Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A et al..  2022.  The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.. Cancers (Basel). 14(20)

van der Mijn JC, Laursen KB, Fu L, Khani F, Dow LE, Nowak DG, Chen Q, Gross SS, Nanus DM, Gudas LJ.  2023.  Novel genetically engineered mouse models for clear cell renal cell carcinoma.. Sci Rep. 13(1):8246.

Patke R, Harris AE, Woodcock CL, Thompson R, Santos R, Kumari A, Allegrucci C, Archer N, Gudas LJ, Robinson BD et al..  2024.  Epitranscriptomic mechanisms of androgen signalling and prostate cancer.. Neoplasia. 56:101032.

DiKun KM, Tang X-H, Fu L, Choi ME, Lu C, Gudas LJ.  2024.  Retinoic acid receptor α activity in proximal tubules prevents kidney injury and fibrosis.. Proc Natl Acad Sci U S A. 121(7):e2311803121.