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Found 55 results
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Year
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2013
Benoit YD
,
Witherspoon MS
,
Laursen KB
,
Guezguez A
,
Beauséjour M
,
Beaulieu J-F
,
Lipkin SM
,
Gudas LJ
. 2013.
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
.
Exp Cell Res. 319(10):1463-70.
Benoit YD
,
Witherspoon MS
,
Laursen KB
,
Guezguez A
,
Beauséjour M
,
Beaulieu J-F
,
Lipkin SM
,
Gudas LJ
. 2013.
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
.
Exp Cell Res. 319(10):1463-70.
Laursen KB
,
Mongan NP
,
Zhuang Y
,
Ng MM
,
Benoit YD
,
Gudas LJ
. 2013.
Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.
.
Nucleic Acids Res. 41(13):6430-43.
Kashyap V
,
Laursen KB
,
Brenet F
,
Viale AJ
,
Scandura JM
,
Gudas LJ
. 2013.
RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.
.
J Cell Sci. 126(Pt 4):999-1008.
2014
Laursen KB
,
Gudas LJ
. 2014.
Crossing the barrier: STRA6 in epidermal differentiation.
.
J Invest Dermatol. 134(6):1504-1506.
Urvalek A
,
Laursen KBruun
,
Gudas LJ
. 2014.
The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes.
.
Subcell Biochem. 70:129-49.
2015
Laursen KB
,
Kashyap V
,
Scandura J
,
Gudas LJ
. 2015.
An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency.
.
J Biol Chem. 290(7):4356-66.
Nilsson EM
,
Laursen KB
,
Whitchurch J
,
McWilliam A
,
Ødum N
,
Persson JL
,
Heery DM
,
Gudas LJ
,
Mongan NP
. 2015.
MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.
.
Oncotarget. 6(34):35710-25.
2018
Quintero CM
,
Laursen KB
,
Mongan NP
,
Luo M
,
Gudas LJ
. 2018.
CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.
.
J Mol Biol. 430(21):4168-4182.
Quintero CM
,
Laursen KB
,
Mongan NP
,
Luo M
,
Gudas LJ
. 2018.
CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.
.
J Mol Biol. 430(21):4168-4182.
Laursen KB
,
Gudas LJ
. 2018.
Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.
.
J Biol Chem. 293(30):11891-11900.
Lee M
,
Gudas LJ
,
Saavedra HI
. 2018.
Detection of E2F-DNA Complexes Using Chromatin Immunoprecipitation Assays.
.
Methods Mol Biol. 1726:143-151.
Marino A
,
Sakamoto T
,
Tang X-H
,
Gudas LJ
,
Levi R
. 2018.
A Retinoic Acid -Receptor Agonist Exerts Cardioprotective Effects.
.
J Pharmacol Exp Ther. 366(2):314-321.
Sureshbabu A
,
Patino E
,
Ma KC
,
Laursen K
,
Finkelsztein EJ
,
Akchurin O
,
Muthukumar T
,
Ryter SW
,
Gudas L
,
Choi AMK
et al.
. 2018.
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction.
.
JCI Insight. 3(11)
2019
Serio RN
,
Lu C
,
Gross SS
,
Gudas LJ
. 2019.
Different Effects of Knockouts in ALDH2 and ACSS2 on Embryonic Stem Cell Differentiation.
.
Alcohol Clin Exp Res. 43(9):1859-1871.
Serio RN
,
Laursen KB
,
Urvalek AM
,
Gross SS
,
Gudas LJ
. 2019.
Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ.
.
J Biol Chem. 294(14):5536-5548.
2021
Laursen KB
,
Chen Q
,
Khani F
,
Attarwala N
,
Gross SS
,
Dow L
,
Nanus DM
,
Gudas LJ
. 2021.
Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma.
.
Front Oncol. 11:783856.
Tang X-H
,
Gambardella J
,
Jankauskas S
,
Wang X
,
Santulli G
,
Gudas LJ
,
Levi R
. 2021.
A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.
.
J Pharmacol Exp Ther. 379(2):182-190.
Tang X-H
,
Melis M
,
Lu C
,
Rappa A
,
Zhang T
,
Jessurun J
,
Gross SS
,
Gudas LJ
. 2021.
A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.
.
J Biol Chem. 297(6):101331.
2022
Benjamin DN
,
O'Donovan TR
,
Laursen KB
,
Orfali N
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2022.
All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.
.
Front Oncol. 12:848517.
Lothion-Roy J
,
Haigh DB
,
Harris AE
,
Metzler VM
,
Alsaleem M
,
Toss MS
,
Kariri Y
,
Ntekim A
,
Robinson BD
,
Khani F
et al.
. 2022.
Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.
.
Front Genet. 13:1096071.
Harris AE
,
Metzler VM
,
Lothion-Roy J
,
Varun D
,
Woodcock CL
,
Haigh DB
,
Endeley C
,
Haque M
,
Toss MS
,
Alsaleem M
et al.
. 2022.
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.
.
Front Endocrinol (Lausanne). 13:1006101.
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Metzler VM
,
Persson JL
,
Robinson BD
,
Khani F
,
Alsaleem M
,
Ntekim A
et al.
. 2022.
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
.
Cancers (Basel). 14(20)
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Metzler VM
,
Persson JL
,
Robinson BD
,
Khani F
,
Alsaleem M
,
Ntekim A
et al.
. 2022.
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
.
Cancers (Basel). 14(20)
van der Mijn JC
,
Chen Q
,
Laursen KB
,
Khani F
,
Wang X
,
Dorsaint P
,
Sboner A
,
Gross SS
,
Nanus DM
,
Gudas LJ
. 2022.
Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR).
.
Mol Carcinog.
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