Publications

Minton DR, Fu L, Chen Q, Robinson BD, Gross SS, Nanus DM, Gudas LJ.  2015.  Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma.. PLoS One. 10(4):e0120649.

Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD et al..  2023.  The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.. Front Cell Dev Biol. 11:1116424.

Melis M, Trasino SE, Tang X-H, Rappa A, Zhang T, Qin L, Gudas LJ.  2023.  Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease.. Int J Mol Sci. 24(15)

Melis M, Tang X-H, Trasino SE, Patel VM, Stummer DJ, Jessurun J, Gudas LJ.  2019.  Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.. PLoS One. 14(1):e0211071.

Melis M, Tang X-H, Trasino SE, Gudas LJ.  2022.  Retinoids in the Pathogenesis and Treatment of Liver Diseases.. Nutrients. 14(7)

Melis M, Tang X-H, Attarwala N, Chen Q, Prishker C, Qin L, Gross SS, Gudas LJ, Trasino SE.  2021.  A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.. Biofactors.

Melis M, Tang X-H, Mai K, Gudas LJ, Trasino SE.  2022.  Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse.. Pharmacology. :1-11.

Martinez-Ceballos E, Gudas LJ.  2008.  Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons.. J Neurosci Res. 86(13):2809-19.

Martinez-Ceballos E, Chambon P, Gudas LJ.  2005.  Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.. J Biol Chem. 280(16):16484-98.

Marta M, Zhang T, Scognamiglio T, Gudas LJ.  2020.  Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma.. Carcinogenesis.

Marino A, Sakamoto T, Tang X-H, Gudas LJ, Levi R.  2018.  A Retinoic Acid -Receptor Agonist Exerts Cardioprotective Effects.. J Pharmacol Exp Ther. 366(2):314-321.

Marcinkiewicz KM, Gudas LJ.  2014.  Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells.. Exp Cell Res. 320(1):128-43.

Marcinkiewicz KM, Gudas LJ.  2014.  Altered histone mark deposition and DNA methylation at homeobox genes in human oral squamous cell carcinoma.. J Cell Physiol. 229(10):1405-16.

Marcinkiewicz K, Scotland KB, Boorjian SA, Nilsson EM, Persson JLiao, Abrahamsson PAnders, Allegrucci C, Hughes IA, Gudas LJ, Mongan NP.  2012.  The androgen receptor and stem cell pathways in prostate and bladder cancers (review).. Int J Oncol. 40(1):5-12.

Malkovskiy AV, Van Wassenhove LD, Goltsev Y, Osei-Sarfo K, Chen C-H, Efron B, Gudas LJ, Mochly-Rosen D, Rajadas J.  2021.  The Effect of Ethanol Consumption on Composition and Morphology of Femur Cortical Bone in Wild-Type and ALDH2*2-Homozygous Mice.. Calcif Tissue Int. 108(2):265-276.

Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F et al..  2022.  Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.. Front Genet. 13:1096071.

Liu L, Gudas LJ.  2002.  Retinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines.. J Cell Physiol. 193(2):244-52.

Liu L, Tang X-H, Scognamiglio T, Gudas LJ.  2010.  Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice.. J Nutr Biochem. 21(10):975-82.

Liu L, Gudas LJ.  2005.  Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency.. J Biol Chem. 280(48):40226-34.

Liu L, Derguini F, Gudas LJ.  2009.  Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells.. J Cell Physiol. 220(3):771-9.

Liu L, Tang X-H, Gudas LJ.  2008.  Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet.. Biochem Pharmacol. 75(12):2316-24.

Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ.  2004.  Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells.. Exp Cell Res. 294(1):290-300.

Lee M, Gudas LJ, Saavedra HI.  2018.  Detection of E2F-DNA Complexes Using Chromatin Immunoprecipitation Assays.. Methods Mol Biol. 1726:143-151.

Lee M-Y, Lu A, Gudas LJ.  2010.  Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells.. J Cell Physiol. 224(1):17-27.

Laursen KB, Mongan NP, Zhuang Y, Ng MM, Benoit YD, Gudas LJ.  2013.  Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.. Nucleic Acids Res. 41(13):6430-43.