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Found 44 results
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2024
Baquero J
,
Tang X-H
,
Ferrotta A
,
Zhang T
,
DiKun KM
,
Gudas LJ
. 2024.
The transcription factor bmi1 increases hypoxic signaling in oral cavity epithelia.
.
Biochim Biophys Acta Mol Basis Dis. :167161.
2022
Benjamin DN
,
O'Donovan TR
,
Laursen KB
,
Orfali N
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2022.
All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.
.
Front Oncol. 12:848517.
Harris AE
,
Metzler VM
,
Lothion-Roy J
,
Varun D
,
Woodcock CL
,
Haigh DB
,
Endeley C
,
Haque M
,
Toss MS
,
Alsaleem M
et al.
. 2022.
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.
.
Front Endocrinol (Lausanne). 13:1006101.
van der Mijn JC
,
Eng KW
,
Chandra P
,
Fernandez E
,
Ramazanoglu S
,
Sigaras A
,
Oromendia C
,
Gudas LJ
,
Tagawa ST
,
Nanus DM
et al.
. 2022.
The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.
.
Mol Oncol.
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Metzler VM
,
Persson JL
,
Robinson BD
,
Khani F
,
Alsaleem M
,
Ntekim A
et al.
. 2022.
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
.
Cancers (Basel). 14(20)
2021
Baquero J
,
Tang X-H
,
Scognamiglio T
,
Gudas LJ
. 2021.
EZH2 knockout in oral cavity basal epithelia causes more invasive squamous cell carcinomas.
.
Carcinogenesis. 42(12):1485-1495.
2020
Orfali N
,
O'Donovan TR
,
Cahill MR
,
Benjamin D
,
Nanus DM
,
McKenna SL
,
Gudas LJ
,
Mongan NP
. 2020.
All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
.
Eur J Haematol. 104(3):236-250.
van der Mijn JC
,
Fu L
,
Khani F
,
Zhang T
,
Molina AM
,
Barbieri CE
,
Chen Q
,
Gross SS
,
Gudas LJ
,
Nanus DM
. 2020.
Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.
.
Transl Oncol. 13(2):177-185.
2019
Orfali N
,
Jeyapalan JN
,
Woodcock CL
,
O'Donovan TR
,
Benjamin D
,
Cahill M
,
McKenna S
,
Gudas LJ
,
Mongan NP
. 2019.
Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.
.
Methods Mol Biol. 2019:33-49.
2015
Orfali N
,
O'Donovan TR
,
Nyhan MJ
,
Britschgi A
,
Tschan MP
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2015.
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.
.
Exp Hematol. 43(9):781-93.e2.
Trasino SE
,
Benoit YD
,
Gudas LJ
. 2015.
Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.
.
J Biol Chem. 290(3):1456-73.
2013
Hedblom A
,
Laursen KB
,
Miftakhova R
,
Sarwar M
,
Anagnostaki L
,
Bredberg A
,
Mongan NP
,
Gudas LJ
,
Persson JL
. 2013.
CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.
.
Cell Cycle. 12(8):1251-66.
Pérez RJ
,
Benoit YD
,
Gudas LJ
. 2013.
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.
.
Exp Cell Res. 319(14):2196-204.
Kopparapu PKumar
,
Boorjian SA
,
Robinson BD
,
Downes M
,
Gudas LJ
,
Mongan NP
,
Persson JL
. 2013.
Expression of cyclin d1 and its association with disease characteristics in bladder cancer.
.
Anticancer Res. 33(12):5235-42.
Kopparapu PKumar
,
Boorjian SA
,
Robinson BD
,
Downes M
,
Gudas LJ
,
Mongan NP
,
Persson JL
. 2013.
Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer.
.
Anticancer Res. 33(6):2381-90.
Benoit YD
,
Laursen KB
,
Witherspoon MS
,
Lipkin SM
,
Gudas LJ
. 2013.
Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
.
J Cell Physiol. 228(4):764-72.
Benoit YD
,
Witherspoon MS
,
Laursen KB
,
Guezguez A
,
Beauséjour M
,
Beaulieu J-F
,
Lipkin SM
,
Gudas LJ
. 2013.
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
.
Exp Cell Res. 319(10):1463-70.
Benoit YD
,
Witherspoon MS
,
Laursen KB
,
Guezguez A
,
Beauséjour M
,
Beaulieu J-F
,
Lipkin SM
,
Gudas LJ
. 2013.
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
.
Exp Cell Res. 319(10):1463-70.
Benoit YD
,
Witherspoon MS
,
Laursen KB
,
Guezguez A
,
Beauséjour M
,
Beaulieu J-F
,
Lipkin SM
,
Gudas LJ
. 2013.
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
.
Exp Cell Res. 319(10):1463-70.
Laursen KB
,
Mongan NP
,
Zhuang Y
,
Ng MM
,
Benoit YD
,
Gudas LJ
. 2013.
Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.
.
Nucleic Acids Res. 41(13):6430-43.
Kashyap V
,
Laursen KB
,
Brenet F
,
Viale AJ
,
Scandura JM
,
Gudas LJ
. 2013.
RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.
.
J Cell Sci. 126(Pt 4):999-1008.
2012
Marcinkiewicz K
,
Scotland KB
,
Boorjian SA
,
Nilsson EM
,
Persson JLiao
,
Abrahamsson PAnders
,
Allegrucci C
,
Hughes IA
,
Gudas LJ
,
Mongan NP
. 2012.
The androgen receptor and stem cell pathways in prostate and bladder cancers (review).
.
Int J Oncol. 40(1):5-12.
Benoit YD
,
Lepage MB
,
Khalfaoui T
,
Tremblay E
,
Basora N
,
Carrier JC
,
Gudas LJ
,
Beaulieu J-F
. 2012.
Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.
.
J Cell Sci. 125(Pt 14):3454-63.
Benoit YD
,
Lepage MB
,
Khalfaoui T
,
Tremblay E
,
Basora N
,
Carrier JC
,
Gudas LJ
,
Beaulieu J-F
. 2012.
Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.
.
J Cell Sci. 125(Pt 14):3454-63.
Benoit YD
,
Lepage MB
,
Khalfaoui T
,
Tremblay E
,
Basora N
,
Carrier JC
,
Gudas LJ
,
Beaulieu J-F
. 2012.
Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.
.
J Cell Sci. 125(Pt 14):3454-63.
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