Publications

Serio RN, Gudas LJ.  2020.  Modification of stem cell states by alcohol and acetaldehyde.. Chem Biol Interact. 316:108919.

Marta M, Zhang T, Scognamiglio T, Gudas LJ.  2020.  Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma.. Carcinogenesis.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Molina AM, van der Mijn JC, Christos P, Wright J, Thomas C, Dutcher JP, Nanus DM, Tagawa ST, Gudas LJ.  2020.  NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.. Invest New Drugs.

Malkovskiy AV, Van Wassenhove LD, Goltsev Y, Osei-Sarfo K, Chen C-H, Efron B, Gudas LJ, Mochly-Rosen D, Rajadas J.  2021.  The Effect of Ethanol Consumption on Composition and Morphology of Femur Cortical Bone in Wild-Type and ALDH2*2-Homozygous Mice.. Calcif Tissue Int. 108(2):265-276.

Baquero J, Tang X-H, Scognamiglio T, Gudas LJ.  2021.  EZH2 knockout in oral cavity basal epithelia causes more invasive squamous cell carcinomas.. Carcinogenesis. 42(12):1485-1495.

Tang X-H, Marta M, Gudas LJ, Mai K, Trasino SE.  2021.  Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease. Front. Pharmacol.

Williams RM, Shah J, Mercer E, Tian HS, Thompson V, Cheung JM, Dorso M, Kubala JM, Gudas LJ, de Stanchina E et al..  2021.  Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury.. Front Pharmacol. 12:790913.

Gudas R, Rimkūnas A, Staškūnas M.  2021.  Large-Diameter Anterior Cruciate Ligament Reconstruction Technique With 8-Strand Semitendinosus and Gracilis Graft.. Arthrosc Tech. 10(4):e981-e986.

Laursen KB, Chen Q, Khani F, Attarwala N, Gross SS, Dow L, Nanus DM, Gudas LJ.  2021.  Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma.. Front Oncol. 11:783856.

Tang X-H, Gambardella J, Jankauskas S, Wang X, Santulli G, Gudas LJ, Levi R.  2021.  A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.. J Pharmacol Exp Ther. 379(2):182-190.

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Melis M, Tang X-H, Attarwala N, Chen Q, Prishker C, Qin L, Gross SS, Gudas LJ, Trasino SE.  2021.  A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.. Biofactors.

Benjamin DN, O'Donovan TR, Laursen KB, Orfali N, Cahill MR, Mongan NP, Gudas LJ, McKenna SL.  2022.  All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.. Front Oncol. 12:848517.

Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F et al..  2022.  Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.. Front Genet. 13:1096071.

Harris AE, Metzler VM, Lothion-Roy J, Varun D, Woodcock CL, Haigh DB, Endeley C, Haque M, Toss MS, Alsaleem M et al..  2022.  Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.. Front Endocrinol (Lausanne). 13:1006101.

Melis M, Tang X-H, Mai K, Gudas LJ, Trasino SE.  2022.  Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse.. Pharmacology. :1-11.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol.

Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A et al..  2022.  The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.. Cancers (Basel). 14(20)

Del Aguila EMere, Tang X-H, Gudas LJ.  2022.  Pancreatic Ductal Adenocarcinoma: New Insights into the Actions of Vitamin A.. Oncol Res Treat.

Gudas LJ.  2022.  Retinoid metabolism: new insights.. J Mol Endocrinol.

Melis M, Tang X-H, Trasino SE, Gudas LJ.  2022.  Retinoids in the Pathogenesis and Treatment of Liver Diseases.. Nutrients. 14(7)

Gudas LJ.  2022.  Synthetic Retinoids Beyond Cancer Therapy.. Annu Rev Pharmacol Toxicol. 62:155-175.

van der Mijn JC, Chen Q, Laursen KB, Khani F, Wang X, Dorsaint P, Sboner A, Gross SS, Nanus DM, Gudas LJ.  2022.  Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR).. Mol Carcinog.

Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD et al..  2023.  The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.. Front Cell Dev Biol. 11:1116424.