Publications

Liu L, Gudas LJ.  2002.  Retinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines.. J Cell Physiol. 193(2):244-52.

Thompson JR, Gudas LJ.  2002.  Retinoic acid induces parietal endoderm but not primitive endoderm and visceral endoderm differentiation in F9 teratocarcinoma stem cells with a targeted deletion of the Rex-1 (Zfp-42) gene.. Mol Cell Endocrinol. 195(1-2):119-33.

Cerignoli F, Guo X, Cardinali B, Rinaldi C, Casaletto J, Frati L, Screpanti I, Gudas LJ, Gulino A, Thiele CJ et al..  2002.  retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines.. Cancer Res. 62(4):1196-204.

Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR.  2003.  Retinoic acid receptor-mediated induction of ABCA1 in macrophages.. Mol Cell Biol. 23(21):7756-66.

Boorjian S, Tickoo SK, Mongan NP, Yu H, Bok D, Rando RR, Nanus DM, Scherr DS, Gudas LJ.  2004.  Reduced lecithin: retinol acyltransferase expression correlates with increased pathologic tumor stage in bladder cancer.. Clin Cancer Res. 10(10):3429-37.

Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ.  2004.  Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells.. Exp Cell Res. 294(1):290-300.

Tighe AP, Gudas LJ.  2004.  Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells.. J Cell Physiol. 198(2):223-9.

Touma SEllen, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM.  2005.  Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.. Clin Cancer Res. 11(9):3558-66.

Boorjian S, Scherr DS, Mongan NP, Zhuang Y, Nanus DM, Gudas LJ.  2005.  Retinoid receptor mRNA expression profiles in human bladder cancer specimens.. Int J Oncol. 26(4):1041-8.

Sheren-Manoff M, Shin SJ, Su D, Bok D, Rando RR, Gudas LJ.  2006.  Reduced lecithin:retinol acyltransferase expression in human breast cancer.. Int J Oncol. 29(5):1193-9.

Gillespie RF, Gudas LJ.  2007.  Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements.. J Biol Chem. 282(46):33421-34.

Gillespie RF, Gudas LJ.  2007.  Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells.. J Mol Biol. 372(2):298-316.

Su D, Gudas LJ.  2008.  Retinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cells.. Exp Hematol. 36(5):624-41.

Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JLiao, Gudas LJ, Mongan NP.  2009.  Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs.. Stem Cells Dev. 18(7):1093-108.

Cai K, Gudas LJ.  2009.  Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene.. Int J Biochem Cell Biol. 41(3):546-53.

Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC et al..  2009.  Retinol saturase promotes adipogenesis and is downregulated in obesity.. Proc Natl Acad Sci U S A. 106(4):1105-10.

Amat R, Gudas LJ.  2011.  RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells.. J Cell Physiol. 226(2):293-8.

Gudas LJ, Wagner JA.  2011.  Retinoids regulate stem cell differentiation.. J Cell Physiol. 226(2):322-30.

Tang X-H, Gudas LJ.  2011.  Retinoids, retinoic acid receptors, and cancer.. Annu Rev Pathol. 6:345-64.

Rezende NC, Lee M-Y, Monette S, Mark W, Lu A, Gudas LJ.  2011.  Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression.. Dev Biol. 356(2):370-82.

Kashyap V, Laursen KB, Brenet F, Viale AJ, Scandura JM, Gudas LJ.  2013.  RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.. J Cell Sci. 126(Pt 4):999-1008.

Gudas LJ.  2013.  Retinoids induce stem cell differentiation via epigenetic changes.. Semin Cell Dev Biol. 24(10-12):701-5.

Urvalek AM, Gudas LJ.  2014.  Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.. J Biol Chem. 289(28):19519-30.

Osei-Sarfo K, Gudas LJ.  2014.  Retinoic acid suppresses the canonical Wnt signaling pathway in embryonic stem cells and activates the noncanonical Wnt signaling pathway.. Stem Cells. 32(8):2061-71.

Orfali N, McKenna SL, Cahill MR, Gudas LJ, Mongan NP.  2014.  Retinoid receptor signaling and autophagy in acute promyelocytic leukemia.. Exp Cell Res. 324(1):1-12.