Publications

Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A et al..  2022.  The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.. Cancers (Basel). 14(20)

Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A et al..  2022.  The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.. Cancers (Basel). 14(20)

Laursen KB, Kashyap V, Scandura J, Gudas LJ.  2015.  An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency.. J Biol Chem. 290(7):4356-66.

Quintero CM, Laursen KB, Mongan NP, Luo M, Gudas LJ.  2018.  CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.. J Mol Biol. 430(21):4168-4182.

Quintero CM, Laursen KB, Mongan NP, Luo M, Gudas LJ.  2018.  CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.. J Mol Biol. 430(21):4168-4182.

Hedblom A, Laursen KB, Miftakhova R, Sarwar M, Anagnostaki L, Bredberg A, Mongan NP, Gudas LJ, Persson JL.  2013.  CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.. Cell Cycle. 12(8):1251-66.

Tang X-H, Suh M-J, Li R, Gudas LJ.  2007.  Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.. J Lipid Res. 48(1):165-76.

Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F et al..  2022.  Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.. Front Genet. 13:1096071.

Laursen KB, Gudas LJ.  2018.  Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.. J Biol Chem. 293(30):11891-11900.

Laursen KB, Gudas LJ.  2014.  Crossing the barrier: STRA6 in epidermal differentiation.. J Invest Dermatol. 134(6):1504-1506.

Langton S, Gudas LJ.  2008.  CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid.. Dev Biol. 315(2):331-54.

Raman JD, Mongan NP, Liu L, Tickoo SK, Nanus DM, Scherr DS, Gudas LJ.  2006.  Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.. Carcinogenesis. 27(3):499-507.

Lee M, Gudas LJ, Saavedra HI.  2018.  Detection of E2F-DNA Complexes Using Chromatin Immunoprecipitation Assays.. Methods Mol Biol. 1726:143-151.

Serio RN, Lu C, Gross SS, Gudas LJ.  2019.  Different Effects of Knockouts in ALDH2 and ACSS2 on Embryonic Stem Cell Differentiation.. Alcohol Clin Exp Res. 43(9):1859-1871.

Liu L, Gudas LJ.  2005.  Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency.. J Biol Chem. 280(48):40226-34.

Laursen KB, Wong P-M, Gudas LJ.  2012.  Epigenetic regulation by RARα maintains ligand-independent transcriptional activity.. Nucleic Acids Res. 40(1):102-15.

Serio RN, Laursen KB, Urvalek AM, Gross SS, Gudas LJ.  2019.  Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ.. J Biol Chem. 294(14):5536-5548.

Harris AE, Metzler VM, Lothion-Roy J, Varun D, Woodcock CL, Haigh DB, Endeley C, Haque M, Toss MS, Alsaleem M et al..  2022.  Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.. Front Endocrinol (Lausanne). 13:1006101.

Liu L, Tang X-H, Gudas LJ.  2008.  Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet.. Biochem Pharmacol. 75(12):2316-24.

Chen AC, Yu K, Lane MA, Gudas LJ.  2003.  Homozygous deletion of the CRABPI gene in AB1 embryonic stem cells results in increased CRABPII gene expression and decreased intracellular retinoic acid concentration.. Arch Biochem Biophys. 411(2):159-73.

Benoit YD, Laursen KB, Witherspoon MS, Lipkin SM, Gudas LJ.  2013.  Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.. J Cell Physiol. 228(4):764-72.

Benoit YD, Laursen KB, Witherspoon MS, Lipkin SM, Gudas LJ.  2013.  Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.. J Cell Physiol. 228(4):764-72.

Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD et al..  2023.  The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.. Front Cell Dev Biol. 11:1116424.

Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD et al..  2023.  The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.. Front Cell Dev Biol. 11:1116424.

Lane MA, Xu J, Wilen EW, Sylvester R, Derguini F, Gudas LJ.  2008.  LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol.. Mol Cell Endocrinol. 280(1-2):63-74.