Publications

Liu L, Derguini F, Gudas LJ.  2009.  Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells.. J Cell Physiol. 220(3):771-9.

Nilsson EM, Laursen KB, Whitchurch J, McWilliam A, Ødum N, Persson JL, Heery DM, Gudas LJ, Mongan NP.  2015.  MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.. Oncotarget. 6(34):35710-25.

Laursen KB, Chen Q, Khani F, Attarwala N, Gross SS, Dow L, Nanus DM, Gudas LJ.  2021.  Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma.. Front Oncol. 11:783856.

Kubala JM, Laursen KB, Schreiner R, Williams RM, van der Mijn JC, Crowley MJ, Mongan NP, Nanus DM, Heller DA, Gudas LJ.  2023.  NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.. Cancer Biol Ther. 24(1):2170669.

van der Mijn JC, Laursen KB, Fu L, Khani F, Dow LE, Nowak DG, Chen Q, Gross SS, Nanus DM, Gudas LJ.  2023.  Novel genetically engineered mouse models for clear cell renal cell carcinoma.. Sci Rep. 13(1):8246.

Liu L, Tang X-H, Scognamiglio T, Gudas LJ.  2010.  Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice.. J Nutr Biochem. 21(10):975-82.

Benoit YD, Witherspoon MS, Laursen KB, Guezguez A, Beauséjour M, Beaulieu J-F, Lipkin SM, Gudas LJ.  2013.  Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.. Exp Cell Res. 319(10):1463-70.

Benoit YD, Witherspoon MS, Laursen KB, Guezguez A, Beauséjour M, Beaulieu J-F, Lipkin SM, Gudas LJ.  2013.  Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.. Exp Cell Res. 319(10):1463-70.

Laursen KB, Mongan NP, Zhuang Y, Ng MM, Benoit YD, Gudas LJ.  2013.  Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.. Nucleic Acids Res. 41(13):6430-43.

Benoit YD, Lepage MB, Khalfaoui T, Tremblay E, Basora N, Carrier JC, Gudas LJ, Beaulieu J-F.  2012.  Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.. J Cell Sci. 125(Pt 14):3454-63.

Kashyap V, Laursen KB, Brenet F, Viale AJ, Scandura JM, Gudas LJ.  2013.  RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.. J Cell Sci. 126(Pt 4):999-1008.

Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ.  2004.  Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells.. Exp Cell Res. 294(1):290-300.

Liu L, Gudas LJ.  2002.  Retinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines.. J Cell Physiol. 193(2):244-52.

Marino A, Sakamoto T, Tang X-H, Gudas LJ, Levi R.  2018.  A Retinoic Acid -Receptor Agonist Exerts Cardioprotective Effects.. J Pharmacol Exp Ther. 366(2):314-321.

DiKun KM, Tang X-H, Fu L, Choi ME, Lu C, Gudas LJ.  2024.  Retinoic acid receptor α activity in proximal tubules prevents kidney injury and fibrosis.. Proc Natl Acad Sci U S A. 121(7):e2311803121.

Tang X-H, Gambardella J, Jankauskas S, Wang X, Santulli G, Gudas LJ, Levi R.  2021.  A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.. J Pharmacol Exp Ther. 379(2):182-190.

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR.  2003.  Retinoic acid receptor-mediated induction of ABCA1 in macrophages.. Mol Cell Biol. 23(21):7756-66.

Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR.  2003.  Retinoic acid receptor-mediated induction of ABCA1 in macrophages.. Mol Cell Biol. 23(21):7756-66.

Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC et al..  2009.  Retinol saturase promotes adipogenesis and is downregulated in obesity.. Proc Natl Acad Sci U S A. 106(4):1105-10.

Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC et al..  2009.  Retinol saturase promotes adipogenesis and is downregulated in obesity.. Proc Natl Acad Sci U S A. 106(4):1105-10.

Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC et al..  2009.  Retinol saturase promotes adipogenesis and is downregulated in obesity.. Proc Natl Acad Sci U S A. 106(4):1105-10.

Rezende NC, Lee M-Y, Monette S, Mark W, Lu A, Gudas LJ.  2011.  Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression.. Dev Biol. 356(2):370-82.

Rezende NC, Lee M-Y, Monette S, Mark W, Lu A, Gudas LJ.  2011.  Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression.. Dev Biol. 356(2):370-82.

Sureshbabu A, Patino E, Ma KC, Laursen K, Finkelsztein EJ, Akchurin O, Muthukumar T, Ryter SW, Gudas L, Choi AMK et al..  2018.  RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction.. JCI Insight. 3(11)