Publications

Tang X-H, Urvalek AM, Osei-Sarfo K, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology.. Oncotarget. 6(27):24424-35.

Tang X-H, Suh M-J, Li R, Gudas LJ.  2007.  Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.. J Lipid Res. 48(1):165-76.

Tang X-H, Osei-Sarfo K, Urvalek AM, Zhang T, Scognamiglio T, Gudas LJ.  2014.  Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Proc Natl Acad Sci U S A. 111(24):8907-12.

Tang X-H, Albert M, Scognamiglio T, Gudas LJ.  2009.  A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Cancer Prev Res (Phila). 2(12):1100-10.

Tang X-H, Su D, Albert M, Scognamiglio T, Gudas LJ.  2009.  Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen.. Cancer Biol Ther. 8(13):1212-3.

Tang X-H, Pesola G, Chen Q, Miller D, Nagy LE, McMullen MR, Schwartz RE, Tsoy S, Lim C, Chikara S et al..  2025.  Ethanol causes rapid decreases in the hepatic retinoid levels shaping the early steps of alcohol-associated liver disease.. Alcohol Clin Exp Res (Hoboken).

Tang X-H, Gudas LJ.  2011.  Retinoids, retinoic acid receptors, and cancer.. Annu Rev Pathol. 6:345-64.

Tang X-H, Gambardella J, Jankauskas S, Wang X, Santulli G, Gudas LJ, Levi R.  2021.  A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.. J Pharmacol Exp Ther. 379(2):182-190.

Tang X-H, Scognamiglio T, Gudas LJ.  2013.  Basal stem cells contribute to squamous cell carcinomas in the oral cavity.. Carcinogenesis. 34(5):1158-64.

Tang X-H, Knudsen B, Bemis D, Tickoo S, Gudas LJ.  2004.  Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.. Clin Cancer Res. 10(1 Pt 1):301-13.

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Tavares TS, Nanus D, Yang XJ, Gudas LJ.  2008.  Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment.. Cancer Biol Ther. 7(10):1607-18.

Thompson JR, Gudas LJ.  2002.  Retinoic acid induces parietal endoderm but not primitive endoderm and visceral endoderm differentiation in F9 teratocarcinoma stem cells with a targeted deletion of the Rex-1 (Zfp-42) gene.. Mol Cell Endocrinol. 195(1-2):119-33.

Tighe AP, Gudas LJ.  2004.  Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells.. J Cell Physiol. 198(2):223-9.

Touma SEllen, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM.  2005.  Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.. Clin Cancer Res. 11(9):3558-66.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2015.  Obesity Leads to Tissue, but not Serum Vitamin A Deficiency.. Sci Rep. 5:15893.

Trasino SE, Gudas LJ.  2015.  Vitamin A: a missing link in diabetes? Diabetes Manag (Lond). 5(5):359-367.

Trasino SE, Benoit YD, Gudas LJ.  2015.  Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.. J Biol Chem. 290(3):1456-73.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2016.  A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.. J Mol Med (Berl). 94(10):1143-1151.

Trasino SE, Tang X-H, Shevchuk MM, Choi ME, Gudas LJ.  2018.  Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor 2 Agonist.. J Pharmacol Exp Ther. 367(1):82-94.

Urvalek AM, Osei-Sarfo K, Tang X-H, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Identification of Ethanol and 4-Nitroquinoline-1-Oxide Induced Epigenetic and Oxidative Stress Markers During Oral Cavity Carcinogenesis.. Alcohol Clin Exp Res. 39(8):1360-72.

Urvalek A, Laursen KBruun, Gudas LJ.  2014.  The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes.. Subcell Biochem. 70:129-49.

Urvalek AM, Gudas LJ.  2014.  Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.. J Biol Chem. 289(28):19519-30.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.