Publications

Tang X-H, Urvalek AM, Osei-Sarfo K, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology.. Oncotarget. 6(27):24424-35.

Tang X-H, Suh M-J, Li R, Gudas LJ.  2007.  Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.. J Lipid Res. 48(1):165-76.

Tang X-H, Osei-Sarfo K, Urvalek AM, Zhang T, Scognamiglio T, Gudas LJ.  2014.  Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Proc Natl Acad Sci U S A. 111(24):8907-12.

Tang X-H, Albert M, Scognamiglio T, Gudas LJ.  2009.  A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Cancer Prev Res (Phila). 2(12):1100-10.

Tang X-H, Su D, Albert M, Scognamiglio T, Gudas LJ.  2009.  Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen.. Cancer Biol Ther. 8(13):1212-3.

Tang X-H, Pesola G, Chen Q, Miller D, Nagy LE, McMullen MR, Schwartz RE, Tsoy S, Lim C, Chikara S et al..  2025.  Ethanol causes rapid decreases in the hepatic retinoid levels shaping the early steps of alcohol-associated liver disease.. Alcohol Clin Exp Res (Hoboken).

Tang X-H, Gudas LJ.  2011.  Retinoids, retinoic acid receptors, and cancer.. Annu Rev Pathol. 6:345-64.

Tang X-H, Gambardella J, Jankauskas S, Wang X, Santulli G, Gudas LJ, Levi R.  2021.  A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.. J Pharmacol Exp Ther. 379(2):182-190.

Tang X-H, Scognamiglio T, Gudas LJ.  2013.  Basal stem cells contribute to squamous cell carcinomas in the oral cavity.. Carcinogenesis. 34(5):1158-64.

Tang X-H, Knudsen B, Bemis D, Tickoo S, Gudas LJ.  2004.  Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.. Clin Cancer Res. 10(1 Pt 1):301-13.

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Tavares TS, Nanus D, Yang XJ, Gudas LJ.  2008.  Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment.. Cancer Biol Ther. 7(10):1607-18.

Thompson JR, Gudas LJ.  2002.  Retinoic acid induces parietal endoderm but not primitive endoderm and visceral endoderm differentiation in F9 teratocarcinoma stem cells with a targeted deletion of the Rex-1 (Zfp-42) gene.. Mol Cell Endocrinol. 195(1-2):119-33.

Tighe AP, Gudas LJ.  2004.  Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells.. J Cell Physiol. 198(2):223-9.

Touma SEllen, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM.  2005.  Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.. Clin Cancer Res. 11(9):3558-66.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2015.  Obesity Leads to Tissue, but not Serum Vitamin A Deficiency.. Sci Rep. 5:15893.

Trasino SE, Gudas LJ.  2015.  Vitamin A: a missing link in diabetes? Diabetes Manag (Lond). 5(5):359-367.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Trasino SE, Benoit YD, Gudas LJ.  2015.  Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.. J Biol Chem. 290(3):1456-73.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2016.  A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.. J Mol Med (Berl). 94(10):1143-1151.

Trasino SE, Tang X-H, Shevchuk MM, Choi ME, Gudas LJ.  2018.  Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor 2 Agonist.. J Pharmacol Exp Ther. 367(1):82-94.

Urvalek AM, Osei-Sarfo K, Tang X-H, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Identification of Ethanol and 4-Nitroquinoline-1-Oxide Induced Epigenetic and Oxidative Stress Markers During Oral Cavity Carcinogenesis.. Alcohol Clin Exp Res. 39(8):1360-72.

Urvalek A, Laursen KBruun, Gudas LJ.  2014.  The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes.. Subcell Biochem. 70:129-49.

Urvalek AM, Gudas LJ.  2014.  Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.. J Biol Chem. 289(28):19519-30.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol.