Publications

Zhang T, Kutler D, Scognamiglio T, Gudas LJ, Tang X-H.  2023.  Transcriptomic analysis predicts the risk of progression of premalignant lesions in human tongue.. Discov Oncol. 14(1):24.

Baquero J, Tang X-H, Ferrotta A, Zhang T, DiKun KM, Gudas LJ.  2024.  The transcription factor bmi1 increases hypoxic signaling in oral cavity epithelia.. Biochim Biophys Acta Mol Basis Dis. :167161.

Suh M-J, Tang X-H, Gudas LJ.  2006.  Structure elucidation of retinoids in biological samples using postsource decay laser desorption/ionization mass spectrometry after high-performance liquid chromatography separation.. Anal Chem. 78(16):5719-28.

Tang X-H, Gudas LJ.  2011.  Retinoids, retinoic acid receptors, and cancer.. Annu Rev Pathol. 6:345-64.

Melis M, Tang X-H, Trasino SE, Gudas LJ.  2022.  Retinoids in the Pathogenesis and Treatment of Liver Diseases.. Nutrients. 14(7)

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2016.  A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.. J Mol Med (Berl). 94(10):1143-1151.

Melis M, Tang X-H, Attarwala N, Chen Q, Prishker C, Qin L, Gross SS, Gudas LJ, Trasino SE.  2021.  A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.. Biofactors.

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Melis M, Trasino SE, Tang X-H, Rappa A, Zhang T, Qin L, Gudas LJ.  2023.  Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease.. Int J Mol Sci. 24(15)

Tang X-H, Gambardella J, Jankauskas S, Wang X, Santulli G, Gudas LJ, Levi R.  2021.  A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.. J Pharmacol Exp Ther. 379(2):182-190.

DiKun KM, Tang X-H, Fu L, Choi ME, Lu C, Gudas LJ.  2024.  Retinoic acid receptor α activity in proximal tubules prevents kidney injury and fibrosis.. Proc Natl Acad Sci U S A. 121(7):e2311803121.

Marino A, Sakamoto T, Tang X-H, Gudas LJ, Levi R.  2018.  A Retinoic Acid -Receptor Agonist Exerts Cardioprotective Effects.. J Pharmacol Exp Ther. 366(2):314-321.

Del Aguila EMere, Tang X-H, Gudas LJ.  2022.  Pancreatic Ductal Adenocarcinoma: New Insights into the Actions of Vitamin A.. Oncol Res Treat.

Tang X-H, Su D, Albert M, Scognamiglio T, Gudas LJ.  2009.  Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen.. Cancer Biol Ther. 8(13):1212-3.

Tang X-H, Vivero M, Gudas LJ.  2008.  Overexpression of CRABPI in suprabasal keratinocytes enhances the proliferation of epidermal basal keratinocytes in mouse skin topically treated with all-trans retinoic acid.. Exp Cell Res. 314(1):38-51.

Tang X-H, Knudsen B, Bemis D, Tickoo S, Gudas LJ.  2004.  Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.. Clin Cancer Res. 10(1 Pt 1):301-13.

Liu L, Tang X-H, Scognamiglio T, Gudas LJ.  2010.  Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice.. J Nutr Biochem. 21(10):975-82.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2015.  Obesity Leads to Tissue, but not Serum Vitamin A Deficiency.. Sci Rep. 5:15893.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Osei-Sarfo K, Tang X-H, Urvalek AM, Scognamiglio T, Gudas LJ.  2013.  The molecular features of tongue epithelium treated with the carcinogen 4-nitroquinoline-1-oxide and alcohol as a model for HNSCC.. Carcinogenesis. 34(11):2673-81.

Osei-Sarfo K, Urvalek AM, Tang X-H, Scognamiglio T, Gudas LJ.  2015.  Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model.. Oncotarget. 6(8):6040-52.

Urvalek AM, Osei-Sarfo K, Tang X-H, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Identification of Ethanol and 4-Nitroquinoline-1-Oxide Induced Epigenetic and Oxidative Stress Markers During Oral Cavity Carcinogenesis.. Alcohol Clin Exp Res. 39(8):1360-72.

Liu L, Tang X-H, Gudas LJ.  2008.  Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet.. Biochem Pharmacol. 75(12):2316-24.

Tang X-H, Urvalek AM, Osei-Sarfo K, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology.. Oncotarget. 6(27):24424-35.

Tang X-H, Marta M, Gudas LJ, Mai K, Trasino SE.  2021.  Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease. Front. Pharmacol.