Publications

Molina AM, van der Mijn JC, Christos P, Wright J, Thomas C, Dutcher JP, Nanus DM, Tagawa ST, Gudas LJ.  2020.  NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.. Invest New Drugs.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Marta M, Zhang T, Scognamiglio T, Gudas LJ.  2020.  Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma.. Carcinogenesis.

Mohn D, Chen SW, Dias DCampos, Weinstein DC, Dyer MA, Sahr K, Ducker CE, Zahradka E, Keller G, Zaret KS et al..  2003.  Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos.. Dev Dyn. 226(3):446-59.

Osei-Sarfo K, Tang X-H, Urvalek AM, Scognamiglio T, Gudas LJ.  2013.  The molecular features of tongue epithelium treated with the carcinogen 4-nitroquinoline-1-oxide and alcohol as a model for HNSCC.. Carcinogenesis. 34(11):2673-81.

Serio RN, Gudas LJ.  2020.  Modification of stem cell states by alcohol and acetaldehyde.. Chem Biol Interact. 316:108919.

Laursen KB, Chen Q, Khani F, Attarwala N, Gross SS, Dow L, Nanus DM, Gudas LJ.  2021.  Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma.. Front Oncol. 11:783856.

Nilsson EM, Laursen KB, Whitchurch J, McWilliam A, Ødum N, Persson JL, Heery DM, Gudas LJ, Mongan NP.  2015.  MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.. Oncotarget. 6(34):35710-25.

Liu L, Derguini F, Gudas LJ.  2009.  Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells.. J Cell Physiol. 220(3):771-9.

Williams RM, Shah J, Ng BD, Minton DR, Gudas LJ, Park CY, Heller DA.  2015.  Mesoscale nanoparticles selectively target the renal proximal tubule epithelium.. Nano Lett. 15(4):2358-64.

Kashyap V, Ahmad S, Nilsson EM, Helczynski L, Kenna S, Persson JLiao, Gudas LJ, Mongan NP.  2013.  The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer.. Mol Oncol. 7(3):555-66.

Lane MA, Xu J, Wilen EW, Sylvester R, Derguini F, Gudas LJ.  2008.  LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol.. Mol Cell Endocrinol. 280(1-2):63-74.

Orfali N, Jeyapalan JN, Woodcock CL, O'Donovan TR, Benjamin D, Cahill M, McKenna S, Gudas LJ, Mongan NP.  2019.  Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.. Methods Mol Biol. 2019:33-49.

Gudas R, Rimkūnas A, Staškūnas M.  2021.  Large-Diameter Anterior Cruciate Ligament Reconstruction Technique With 8-Strand Semitendinosus and Gracilis Graft.. Arthrosc Tech. 10(4):e981-e986.

Williams RM, Shah J, Mercer E, Tian HS, Thompson V, Cheung JM, Dorso M, Kubala JM, Gudas LJ, de Stanchina E et al..  2021.  Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury.. Front Pharmacol. 12:790913.

Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD et al..  2023.  The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.. Front Cell Dev Biol. 11:1116424.

Osei-Sarfo K, Urvalek AM, Tang X-H, Scognamiglio T, Gudas LJ.  2015.  Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model.. Oncotarget. 6(8):6040-52.

Orfali N, Shan-Krauer D, O'Donovan TR, Mongan NP, Gudas LJ, Cahill MR, Tschan MP, McKenna SL.  2019.  Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.. Mol Oncol.

Benoit YD, Laursen KB, Witherspoon MS, Lipkin SM, Gudas LJ.  2013.  Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.. J Cell Physiol. 228(4):764-72.

Reynertson KA, Charlson ME, Gudas LJ.  2011.  Induction of murine embryonic stem cell differentiation by medicinal plant extracts.. Exp Cell Res. 317(1):82-93.

Orfali N, O'Donovan TR, Nyhan MJ, Britschgi A, Tschan MP, Cahill MR, Mongan NP, Gudas LJ, McKenna SL.  2015.  Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.. Exp Hematol. 43(9):781-93.e2.

Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ.  2005.  Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.. Clin Cancer Res. 11(24 Pt 1):8570-6.

Urvalek AM, Osei-Sarfo K, Tang X-H, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Identification of Ethanol and 4-Nitroquinoline-1-Oxide Induced Epigenetic and Oxidative Stress Markers During Oral Cavity Carcinogenesis.. Alcohol Clin Exp Res. 39(8):1360-72.

Zhuang Y, Faria TN, Chambon P, Gudas LJ.  2003.  Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells.. Mol Cancer Res. 1(8):619-30.

Martinez-Ceballos E, Gudas LJ.  2008.  Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons.. J Neurosci Res. 86(13):2809-19.