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Found 34 results
Author
Title
Type
Year
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Mongan, Nigel P
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2024
Patke R
,
Harris AE
,
Woodcock CL
,
Thompson R
,
Santos R
,
Kumari A
,
Allegrucci C
,
Archer N
,
Gudas LJ
,
Robinson BD
et al.
. 2024.
Epitranscriptomic mechanisms of androgen signalling and prostate cancer.
.
Neoplasia. 56:101032.
2023
Metzler VM
,
de Brot S
,
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Nilsson EM
,
Ntekim A
,
Persson JL
,
Robinson BD
et al.
. 2023.
The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.
.
Front Cell Dev Biol. 11:1116424.
Kubala JM
,
Laursen KB
,
Schreiner R
,
Williams RM
,
van der Mijn JC
,
Crowley MJ
,
Mongan NP
,
Nanus DM
,
Heller DA
,
Gudas LJ
. 2023.
NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.
.
Cancer Biol Ther. 24(1):2170669.
2022
Benjamin DN
,
O'Donovan TR
,
Laursen KB
,
Orfali N
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2022.
All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.
.
Front Oncol. 12:848517.
Lothion-Roy J
,
Haigh DB
,
Harris AE
,
Metzler VM
,
Alsaleem M
,
Toss MS
,
Kariri Y
,
Ntekim A
,
Robinson BD
,
Khani F
et al.
. 2022.
Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.
.
Front Genet. 13:1096071.
Harris AE
,
Metzler VM
,
Lothion-Roy J
,
Varun D
,
Woodcock CL
,
Haigh DB
,
Endeley C
,
Haque M
,
Toss MS
,
Alsaleem M
et al.
. 2022.
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.
.
Front Endocrinol (Lausanne). 13:1006101.
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Metzler VM
,
Persson JL
,
Robinson BD
,
Khani F
,
Alsaleem M
,
Ntekim A
et al.
. 2022.
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
.
Cancers (Basel). 14(20)
2020
Orfali N
,
O'Donovan TR
,
Cahill MR
,
Benjamin D
,
Nanus DM
,
McKenna SL
,
Gudas LJ
,
Mongan NP
. 2020.
All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
.
Eur J Haematol. 104(3):236-250.
2019
Orfali N
,
Shan-Krauer D
,
O'Donovan TR
,
Mongan NP
,
Gudas LJ
,
Cahill MR
,
Tschan MP
,
McKenna SL
. 2019.
Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.
.
Mol Oncol.
Orfali N
,
Jeyapalan JN
,
Woodcock CL
,
O'Donovan TR
,
Benjamin D
,
Cahill M
,
McKenna S
,
Gudas LJ
,
Mongan NP
. 2019.
Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.
.
Methods Mol Biol. 2019:33-49.
2018
Quintero CM
,
Laursen KB
,
Mongan NP
,
Luo M
,
Gudas LJ
. 2018.
CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.
.
J Mol Biol. 430(21):4168-4182.
2016
Minton DR
,
Fu L
,
Mongan NP
,
Shevchuk MM
,
Nanus DM
,
Gudas LJ
. 2016.
Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma.
.
Clin Cancer Res. 22(11):2791-801.
2015
Orfali N
,
O'Donovan TR
,
Nyhan MJ
,
Britschgi A
,
Tschan MP
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2015.
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.
.
Exp Hematol. 43(9):781-93.e2.
Nilsson EM
,
Laursen KB
,
Whitchurch J
,
McWilliam A
,
Ødum N
,
Persson JL
,
Heery DM
,
Gudas LJ
,
Mongan NP
. 2015.
MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.
.
Oncotarget. 6(34):35710-25.
2014
Orfali N
,
McKenna SL
,
Cahill MR
,
Gudas LJ
,
Mongan NP
. 2014.
Retinoid receptor signaling and autophagy in acute promyelocytic leukemia.
.
Exp Cell Res. 324(1):1-12.
Gudas LJ
,
Fu L
,
Minton DR
,
Mongan NP
,
Nanus DM
. 2014.
The role of HIF1α in renal cell carcinoma tumorigenesis.
.
J Mol Med (Berl). 92(8):825-36.
2013
Hedblom A
,
Laursen KB
,
Miftakhova R
,
Sarwar M
,
Anagnostaki L
,
Bredberg A
,
Mongan NP
,
Gudas LJ
,
Persson JL
. 2013.
CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.
.
Cell Cycle. 12(8):1251-66.
Kauffman EC
,
Robinson BD
,
Downes M
,
Marcinkiewicz K
,
Vourganti S
,
Scherr DS
,
Gudas LJ
,
Mongan NP
. 2013.
Estrogen receptor-β expression and pharmacological targeting in bladder cancer.
.
Oncol Rep. 30(1):131-8.
Kopparapu PKumar
,
Boorjian SA
,
Robinson BD
,
Downes M
,
Gudas LJ
,
Mongan NP
,
Persson JL
. 2013.
Expression of cyclin d1 and its association with disease characteristics in bladder cancer.
.
Anticancer Res. 33(12):5235-42.
Kopparapu PKumar
,
Boorjian SA
,
Robinson BD
,
Downes M
,
Gudas LJ
,
Mongan NP
,
Persson JL
. 2013.
Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer.
.
Anticancer Res. 33(6):2381-90.
Kashyap V
,
Ahmad S
,
Nilsson EM
,
Helczynski L
,
Kenna S
,
Persson JLiao
,
Gudas LJ
,
Mongan NP
. 2013.
The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer.
.
Mol Oncol. 7(3):555-66.
Laursen KB
,
Mongan NP
,
Zhuang Y
,
Ng MM
,
Benoit YD
,
Gudas LJ
. 2013.
Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.
.
Nucleic Acids Res. 41(13):6430-43.
2012
Marcinkiewicz K
,
Scotland KB
,
Boorjian SA
,
Nilsson EM
,
Persson JLiao
,
Abrahamsson PAnders
,
Allegrucci C
,
Hughes IA
,
Gudas LJ
,
Mongan NP
. 2012.
The androgen receptor and stem cell pathways in prostate and bladder cancers (review).
.
Int J Oncol. 40(1):5-12.
2010
David KA
,
Mongan NP
,
Smith C
,
Gudas LJ
,
Nanus DM
. 2010.
Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.
.
Cancer Biol Ther. 9(9):678-84.
2009
Kashyap V
,
Rezende NC
,
Scotland KB
,
Shaffer SM
,
Persson JLiao
,
Gudas LJ
,
Mongan NP
. 2009.
Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs.
.
Stem Cells Dev. 18(7):1093-108.
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