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Found 34 results
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Mongan, Nigel P
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A
Orfali N
,
O'Donovan TR
,
Cahill MR
,
Benjamin D
,
Nanus DM
,
McKenna SL
,
Gudas LJ
,
Mongan NP
. 2020.
All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
.
Eur J Haematol. 104(3):236-250.
Benjamin DN
,
O'Donovan TR
,
Laursen KB
,
Orfali N
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2022.
All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.
.
Front Oncol. 12:848517.
Marcinkiewicz K
,
Scotland KB
,
Boorjian SA
,
Nilsson EM
,
Persson JLiao
,
Abrahamsson PAnders
,
Allegrucci C
,
Hughes IA
,
Gudas LJ
,
Mongan NP
. 2012.
The androgen receptor and stem cell pathways in prostate and bladder cancers (review).
.
Int J Oncol. 40(1):5-12.
Boorjian S
,
Ugras S
,
Mongan NP
,
Gudas LJ
,
You X
,
Tickoo SK
,
Scherr DS
. 2004.
Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.
.
Urology. 64(2):383-8.
C
Quintero CM
,
Laursen KB
,
Mongan NP
,
Luo M
,
Gudas LJ
. 2018.
CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.
.
J Mol Biol. 430(21):4168-4182.
Hedblom A
,
Laursen KB
,
Miftakhova R
,
Sarwar M
,
Anagnostaki L
,
Bredberg A
,
Mongan NP
,
Gudas LJ
,
Persson JL
. 2013.
CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.
.
Cell Cycle. 12(8):1251-66.
Lothion-Roy J
,
Haigh DB
,
Harris AE
,
Metzler VM
,
Alsaleem M
,
Toss MS
,
Kariri Y
,
Ntekim A
,
Robinson BD
,
Khani F
et al.
. 2022.
Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.
.
Front Genet. 13:1096071.
D
Raman JD
,
Mongan NP
,
Liu L
,
Tickoo SK
,
Nanus DM
,
Scherr DS
,
Gudas LJ
. 2006.
Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.
.
Carcinogenesis. 27(3):499-507.
Mongan NP
,
Gudas LJ
. 2007.
Diverse actions of retinoid receptors in cancer prevention and treatment.
.
Differentiation. 75(9):853-70.
E
Patke R
,
Harris AE
,
Woodcock CL
,
Thompson R
,
Santos R
,
Kumari A
,
Allegrucci C
,
Archer N
,
Gudas LJ
,
Robinson BD
et al.
. 2024.
Epitranscriptomic mechanisms of androgen signalling and prostate cancer.
.
Neoplasia. 56:101032.
Kauffman EC
,
Robinson BD
,
Downes M
,
Marcinkiewicz K
,
Vourganti S
,
Scherr DS
,
Gudas LJ
,
Mongan NP
. 2013.
Estrogen receptor-β expression and pharmacological targeting in bladder cancer.
.
Oncol Rep. 30(1):131-8.
Harris AE
,
Metzler VM
,
Lothion-Roy J
,
Varun D
,
Woodcock CL
,
Haigh DB
,
Endeley C
,
Haque M
,
Toss MS
,
Alsaleem M
et al.
. 2022.
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.
.
Front Endocrinol (Lausanne). 13:1006101.
Kopparapu PKumar
,
Boorjian SA
,
Robinson BD
,
Downes M
,
Gudas LJ
,
Mongan NP
,
Persson JL
. 2013.
Expression of cyclin d1 and its association with disease characteristics in bladder cancer.
.
Anticancer Res. 33(12):5235-42.
Kopparapu PKumar
,
Boorjian SA
,
Robinson BD
,
Downes M
,
Gudas LJ
,
Mongan NP
,
Persson JL
. 2013.
Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer.
.
Anticancer Res. 33(6):2381-90.
I
Raman JD
,
Mongan NP
,
Tickoo SK
,
Boorjian SA
,
Scherr DS
,
Gudas LJ
. 2005.
Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.
.
Clin Cancer Res. 11(24 Pt 1):8570-6.
Orfali N
,
O'Donovan TR
,
Nyhan MJ
,
Britschgi A
,
Tschan MP
,
Cahill MR
,
Mongan NP
,
Gudas LJ
,
McKenna SL
. 2015.
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.
.
Exp Hematol. 43(9):781-93.e2.
Orfali N
,
Shan-Krauer D
,
O'Donovan TR
,
Mongan NP
,
Gudas LJ
,
Cahill MR
,
Tschan MP
,
McKenna SL
. 2019.
Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.
.
Mol Oncol.
K
Metzler VM
,
de Brot S
,
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Nilsson EM
,
Ntekim A
,
Persson JL
,
Robinson BD
et al.
. 2023.
The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.
.
Front Cell Dev Biol. 11:1116424.
L
Orfali N
,
Jeyapalan JN
,
Woodcock CL
,
O'Donovan TR
,
Benjamin D
,
Cahill M
,
McKenna S
,
Gudas LJ
,
Mongan NP
. 2019.
Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.
.
Methods Mol Biol. 2019:33-49.
Kashyap V
,
Ahmad S
,
Nilsson EM
,
Helczynski L
,
Kenna S
,
Persson JLiao
,
Gudas LJ
,
Mongan NP
. 2013.
The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer.
.
Mol Oncol. 7(3):555-66.
M
Haigh DB
,
Woodcock CL
,
Lothion-Roy J
,
Harris AE
,
Metzler VM
,
Persson JL
,
Robinson BD
,
Khani F
,
Alsaleem M
,
Ntekim A
et al.
. 2022.
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
.
Cancers (Basel). 14(20)
Nilsson EM
,
Laursen KB
,
Whitchurch J
,
McWilliam A
,
Ødum N
,
Persson JL
,
Heery DM
,
Gudas LJ
,
Mongan NP
. 2015.
MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.
.
Oncotarget. 6(34):35710-25.
N
Kubala JM
,
Laursen KB
,
Schreiner R
,
Williams RM
,
van der Mijn JC
,
Crowley MJ
,
Mongan NP
,
Nanus DM
,
Heller DA
,
Gudas LJ
. 2023.
NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.
.
Cancer Biol Ther. 24(1):2170669.
P
Boorjian SA
,
Milowsky MI
,
Kaplan J
,
Albert M
,
Cobham MVallee
,
Coll DM
,
Mongan NP
,
Shelton G
,
Petrylak D
,
Gudas LJ
et al.
. 2007.
Phase 1/2 clinical trial of interferon alpha2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma.
.
J Immunother. 30(6):655-62.
David KA
,
Mongan NP
,
Smith C
,
Gudas LJ
,
Nanus DM
. 2010.
Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.
.
Cancer Biol Ther. 9(9):678-84.
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