Publications

Orfali N, O'Donovan TR, Cahill MR, Benjamin D, Nanus DM, McKenna SL, Gudas LJ, Mongan NP.  2020.  All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).. Eur J Haematol. 104(3):236-250.

Benjamin DN, O'Donovan TR, Laursen KB, Orfali N, Cahill MR, Mongan NP, Gudas LJ, McKenna SL.  2022.  All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism.. Front Oncol. 12:848517.

Marcinkiewicz K, Scotland KB, Boorjian SA, Nilsson EM, Persson JLiao, Abrahamsson PAnders, Allegrucci C, Hughes IA, Gudas LJ, Mongan NP.  2012.  The androgen receptor and stem cell pathways in prostate and bladder cancers (review).. Int J Oncol. 40(1):5-12.

Boorjian S, Ugras S, Mongan NP, Gudas LJ, You X, Tickoo SK, Scherr DS.  2004.  Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.. Urology. 64(2):383-8.

Hedblom A, Laursen KB, Miftakhova R, Sarwar M, Anagnostaki L, Bredberg A, Mongan NP, Gudas LJ, Persson JL.  2013.  CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.. Cell Cycle. 12(8):1251-66.

Brennan EP, Tang X-H, Stewart-Akers AM, Gudas LJ, Badylak SF.  2008.  Chemoattractant activity of degradation products of fetal and adult skin extracellular matrix for keratinocyte progenitor cells.. J Tissue Eng Regen Med. 2(8):491-8.

Brennan EP, Tang X-H, Stewart-Akers AM, Gudas LJ, Badylak SF.  2008.  Chemoattractant activity of degradation products of fetal and adult skin extracellular matrix for keratinocyte progenitor cells.. J Tissue Eng Regen Med. 2(8):491-8.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.

Pérez RJ, Benoit YD, Gudas LJ.  2013.  Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.. Exp Cell Res. 319(14):2196-204.

Zhan HChun, Gudas LJ, Bok D, Rando R, Nanus DM, Tickoo SK.  2003.  Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney.. Clin Cancer Res. 9(13):4897-905.

Wang G, Badylak SF, Heber-Katz E, Braunhut SJ, Gudas LJ.  2010.  The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.. Regen Med. 5(2):201-20.

Wang G, Badylak SF, Heber-Katz E, Braunhut SJ, Gudas LJ.  2010.  The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.. Regen Med. 5(2):201-20.

Kashyap V, Gudas LJ, Brenet F, Funk P, Viale A, Scandura JM.  2011.  Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid.. J Biol Chem. 286(5):3250-60.

Agrawal V, Johnson SA, Reing J, Zhang L, Tottey S, Wang G, Hirschi KK, Braunhut S, Gudas LJ, Badylak SF.  2010.  Epimorphic regeneration approach to tissue replacement in adult mammals.. Proc Natl Acad Sci U S A. 107(8):3351-5.

Agrawal V, Johnson SA, Reing J, Zhang L, Tottey S, Wang G, Hirschi KK, Braunhut S, Gudas LJ, Badylak SF.  2010.  Epimorphic regeneration approach to tissue replacement in adult mammals.. Proc Natl Acad Sci U S A. 107(8):3351-5.

Harris AE, Metzler VM, Lothion-Roy J, Varun D, Woodcock CL, Haigh DB, Endeley C, Haque M, Toss MS, Alsaleem M et al..  2022.  Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.. Front Endocrinol (Lausanne). 13:1006101.

Kopparapu PKumar, Boorjian SA, Robinson BD, Downes M, Gudas LJ, Mongan NP, Persson JL.  2013.  Expression of cyclin d1 and its association with disease characteristics in bladder cancer.. Anticancer Res. 33(12):5235-42.

Kopparapu PKumar, Boorjian SA, Robinson BD, Downes M, Gudas LJ, Mongan NP, Persson JL.  2013.  Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer.. Anticancer Res. 33(6):2381-90.

Baquero J, Tang X-H, Scognamiglio T, Gudas LJ.  2021.  EZH2 knockout in oral cavity basal epithelia causes more invasive squamous cell carcinomas.. Carcinogenesis. 42(12):1485-1495.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol.

Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ.  2005.  Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.. Clin Cancer Res. 11(24 Pt 1):8570-6.

Orfali N, O'Donovan TR, Nyhan MJ, Britschgi A, Tschan MP, Cahill MR, Mongan NP, Gudas LJ, McKenna SL.  2015.  Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.. Exp Hematol. 43(9):781-93.e2.

Benoit YD, Laursen KB, Witherspoon MS, Lipkin SM, Gudas LJ.  2013.  Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.. J Cell Physiol. 228(4):764-72.

Orfali N, Jeyapalan JN, Woodcock CL, O'Donovan TR, Benjamin D, Cahill M, McKenna S, Gudas LJ, Mongan NP.  2019.  Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.. Methods Mol Biol. 2019:33-49.

Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A et al..  2022.  The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.. Cancers (Basel). 14(20)