Publications

Langton S, Gudas LJ.  2008.  CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid.. Dev Biol. 315(2):331-54.

Su D, Gudas LJ.  2008.  Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells.. Biochem Pharmacol. 75(5):1129-60.

Tavares TS, Nanus D, Yang XJ, Gudas LJ.  2008.  Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment.. Cancer Biol Ther. 7(10):1607-18.

Liu L, Tang X-H, Gudas LJ.  2008.  Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet.. Biochem Pharmacol. 75(12):2316-24.

Martinez-Ceballos E, Gudas LJ.  2008.  Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons.. J Neurosci Res. 86(13):2809-19.

Lane MA, Xu J, Wilen EW, Sylvester R, Derguini F, Gudas LJ.  2008.  LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol.. Mol Cell Endocrinol. 280(1-2):63-74.

Zhuang Y, Gudas LJ.  2008.  Overexpression of COUP-TF1 in murine embryonic stem cells reduces retinoic acid-associated growth arrest and increases extraembryonic endoderm gene expression.. Differentiation. 76(7):760-71.

Tang X-H, Vivero M, Gudas LJ.  2008.  Overexpression of CRABPI in suprabasal keratinocytes enhances the proliferation of epidermal basal keratinocytes in mouse skin topically treated with all-trans retinoic acid.. Exp Cell Res. 314(1):38-51.

Su D, Gudas LJ.  2008.  Retinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cells.. Exp Hematol. 36(5):624-41.

Xu J, Sylvester R, Tighe AP, Chen S, Gudas LJ.  2008.  Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells.. J Mol Biol. 377(1):28-46.

Tang X-H, Suh M-J, Li R, Gudas LJ.  2007.  Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.. J Lipid Res. 48(1):165-76.

Mongan NP, Gudas LJ.  2007.  Diverse actions of retinoid receptors in cancer prevention and treatment.. Differentiation. 75(9):853-70.

Boorjian SA, Milowsky MI, Kaplan J, Albert M, Cobham MVallee, Coll DM, Mongan NP, Shelton G, Petrylak D, Gudas LJ et al..  2007.  Phase 1/2 clinical trial of interferon alpha2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma.. J Immunother. 30(6):655-62.

Gillespie RF, Gudas LJ.  2007.  Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements.. J Biol Chem. 282(46):33421-34.

Gillespie RF, Gudas LJ.  2007.  Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells.. J Mol Biol. 372(2):298-316.

Raman JD, Mongan NP, Liu L, Tickoo SK, Nanus DM, Scherr DS, Gudas LJ.  2006.  Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.. Carcinogenesis. 27(3):499-507.

Mongan NP, Martin KM, Gudas LJ.  2006.  The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures.. Mol Carcinog. 45(12):887-900.

Sheren-Manoff M, Shin SJ, Su D, Bok D, Rando RR, Gudas LJ.  2006.  Reduced lecithin:retinol acyltransferase expression in human breast cancer.. Int J Oncol. 29(5):1193-9.

Gudas LJ.  2006.  Stem cells, differentiation and cancer: mentors, colleagues and academic administration.. Cancer Biol Ther. 5(9):1244-6.

Suh M-J, Tang X-H, Gudas LJ.  2006.  Structure elucidation of retinoids in biological samples using postsource decay laser desorption/ionization mass spectrometry after high-performance liquid chromatography separation.. Anal Chem. 78(16):5719-28.

Martinez-Ceballos E, Chambon P, Gudas LJ.  2005.  Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.. J Biol Chem. 280(16):16484-98.

Liu L, Gudas LJ.  2005.  Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency.. J Biol Chem. 280(48):40226-34.

Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ.  2005.  Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.. Clin Cancer Res. 11(24 Pt 1):8570-6.

Touma SEllen, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM.  2005.  Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.. Clin Cancer Res. 11(9):3558-66.

Boorjian S, Scherr DS, Mongan NP, Zhuang Y, Nanus DM, Gudas LJ.  2005.  Retinoid receptor mRNA expression profiles in human bladder cancer specimens.. Int J Oncol. 26(4):1041-8.