Publications

Kashyap V, Gudas LJ, Brenet F, Funk P, Viale A, Scandura JM.  2011.  Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid.. J Biol Chem. 286(5):3250-60.

Kashyap V, Gudas LJ.  2010.  Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts.. J Biol Chem. 285(19):14534-48.

Laursen KB, Wong P-M, Gudas LJ.  2012.  Epigenetic regulation by RARα maintains ligand-independent transcriptional activity.. Nucleic Acids Res. 40(1):102-15.

Gudas LJ.  2012.  Emerging roles for retinoids in regeneration and differentiation in normal and disease states.. Biochim Biophys Acta. 1821(1):213-21.

Wang G, Badylak SF, Heber-Katz E, Braunhut SJ, Gudas LJ.  2010.  The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.. Regen Med. 5(2):201-20.

Melis M, Tang X-H, Trasino SE, Patel VM, Stummer DJ, Jessurun J, Gudas LJ.  2019.  Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.. PLoS One. 14(1):e0211071.

Malkovskiy AV, Van Wassenhove LD, Goltsev Y, Osei-Sarfo K, Chen C-H, Efron B, Gudas LJ, Mochly-Rosen D, Rajadas J.  2021.  The Effect of Ethanol Consumption on Composition and Morphology of Femur Cortical Bone in Wild-Type and ALDH2*2-Homozygous Mice.. Calcif Tissue Int. 108(2):265-276.

Kalish JM, Tang X-H, Scognamiglio T, Zhang T, Gudas LJ.  2020.  Doxycycline-induced exogenous Bmi-1 expression enhances tumor formation in a murine model of oral squamous cell carcinoma.. Cancer Biol Ther. :1-12.

Tang X-H, Albert M, Scognamiglio T, Gudas LJ.  2009.  A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Cancer Prev Res (Phila). 2(12):1100-10.

Mongan NP, Gudas LJ.  2007.  Diverse actions of retinoid receptors in cancer prevention and treatment.. Differentiation. 75(9):853-70.

Liu L, Gudas LJ.  2005.  Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency.. J Biol Chem. 280(48):40226-34.

Zhan HChun, Gudas LJ, Bok D, Rando R, Nanus DM, Tickoo SK.  2003.  Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney.. Clin Cancer Res. 9(13):4897-905.

Serio RN, Lu C, Gross SS, Gudas LJ.  2019.  Different Effects of Knockouts in ALDH2 and ACSS2 on Embryonic Stem Cell Differentiation.. Alcohol Clin Exp Res. 43(9):1859-1871.

Martinez-Ceballos E, Chambon P, Gudas LJ.  2005.  Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.. J Biol Chem. 280(16):16484-98.

Lee M, Gudas LJ, Saavedra HI.  2018.  Detection of E2F-DNA Complexes Using Chromatin Immunoprecipitation Assays.. Methods Mol Biol. 1726:143-151.

Chi Y, Chikara S, Del Aguila EMere, Zhang T, Geri JB, Nanus DM, Gudas LJ.  2025.  Deletion of the transcription factor ATF4 in a model of clear cell renal cell carcinoma.. Neoplasia. 66:101188.

Pérez RJ, Benoit YD, Gudas LJ.  2013.  Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.. Exp Cell Res. 319(14):2196-204.

Raman JD, Mongan NP, Liu L, Tickoo SK, Nanus DM, Scherr DS, Gudas LJ.  2006.  Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.. Carcinogenesis. 27(3):499-507.

Ricard MJ, Gudas LJ.  2013.  Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells.. J Biol Chem. 288(40):28801-13.

Langton S, Gudas LJ.  2008.  CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid.. Dev Biol. 315(2):331-54.

Laursen KB, Gudas LJ.  2014.  Crossing the barrier: STRA6 in epidermal differentiation.. J Invest Dermatol. 134(6):1504-1506.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.

Laursen KB, Gudas LJ.  2018.  Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.. J Biol Chem. 293(30):11891-11900.

Tang X-H, Osei-Sarfo K, Urvalek AM, Zhang T, Scognamiglio T, Gudas LJ.  2014.  Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.. Proc Natl Acad Sci U S A. 111(24):8907-12.

Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F et al..  2022.  Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.. Front Genet. 13:1096071.