Publications

Tang X-H, Suh M-J, Li R, Gudas LJ.  2007.  Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.. J Lipid Res. 48(1):165-76.

Mongan NP, Gudas LJ.  2007.  Diverse actions of retinoid receptors in cancer prevention and treatment.. Differentiation. 75(9):853-70.

Boorjian SA, Milowsky MI, Kaplan J, Albert M, Cobham MVallee, Coll DM, Mongan NP, Shelton G, Petrylak D, Gudas LJ et al..  2007.  Phase 1/2 clinical trial of interferon alpha2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma.. J Immunother. 30(6):655-62.

Gillespie RF, Gudas LJ.  2007.  Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements.. J Biol Chem. 282(46):33421-34.

Gillespie RF, Gudas LJ.  2007.  Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells.. J Mol Biol. 372(2):298-316.

Raman JD, Mongan NP, Liu L, Tickoo SK, Nanus DM, Scherr DS, Gudas LJ.  2006.  Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.. Carcinogenesis. 27(3):499-507.

Mongan NP, Martin KM, Gudas LJ.  2006.  The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures.. Mol Carcinog. 45(12):887-900.

Sheren-Manoff M, Shin SJ, Su D, Bok D, Rando RR, Gudas LJ.  2006.  Reduced lecithin:retinol acyltransferase expression in human breast cancer.. Int J Oncol. 29(5):1193-9.

Gudas LJ.  2006.  Stem cells, differentiation and cancer: mentors, colleagues and academic administration.. Cancer Biol Ther. 5(9):1244-6.

Suh M-J, Tang X-H, Gudas LJ.  2006.  Structure elucidation of retinoids in biological samples using postsource decay laser desorption/ionization mass spectrometry after high-performance liquid chromatography separation.. Anal Chem. 78(16):5719-28.

Martinez-Ceballos E, Chambon P, Gudas LJ.  2005.  Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.. J Biol Chem. 280(16):16484-98.

Liu L, Gudas LJ.  2005.  Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency.. J Biol Chem. 280(48):40226-34.

Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ.  2005.  Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.. Clin Cancer Res. 11(24 Pt 1):8570-6.

Touma SEllen, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM.  2005.  Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.. Clin Cancer Res. 11(9):3558-66.

Boorjian S, Scherr DS, Mongan NP, Zhuang Y, Nanus DM, Gudas LJ.  2005.  Retinoid receptor mRNA expression profiles in human bladder cancer specimens.. Int J Oncol. 26(4):1041-8.

Mongan NP, Gudas LJ.  2005.  Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.. Mol Cancer Ther. 4(3):477-86.

Boorjian S, Ugras S, Mongan NP, Gudas LJ, You X, Tickoo SK, Scherr DS.  2004.  Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.. Urology. 64(2):383-8.

Tang X-H, Knudsen B, Bemis D, Tickoo S, Gudas LJ.  2004.  Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.. Clin Cancer Res. 10(1 Pt 1):301-13.

Boorjian S, Tickoo SK, Mongan NP, Yu H, Bok D, Rando RR, Nanus DM, Scherr DS, Gudas LJ.  2004.  Reduced lecithin: retinol acyltransferase expression correlates with increased pathologic tumor stage in bladder cancer.. Clin Cancer Res. 10(10):3429-37.

Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ.  2004.  Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells.. Exp Cell Res. 294(1):290-300.

Tighe AP, Gudas LJ.  2004.  Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells.. J Cell Physiol. 198(2):223-9.

Zhan HChun, Gudas LJ, Bok D, Rando R, Nanus DM, Tickoo SK.  2003.  Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney.. Clin Cancer Res. 9(13):4897-905.

Chen AC, Yu K, Lane MA, Gudas LJ.  2003.  Homozygous deletion of the CRABPI gene in AB1 embryonic stem cells results in increased CRABPII gene expression and decreased intracellular retinoic acid concentration.. Arch Biochem Biophys. 411(2):159-73.

Zhuang Y, Faria TN, Chambon P, Gudas LJ.  2003.  Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells.. Mol Cancer Res. 1(8):619-30.

Mohn D, Chen SW, Dias DCampos, Weinstein DC, Dyer MA, Sahr K, Ducker CE, Zahradka E, Keller G, Zaret KS et al..  2003.  Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos.. Dev Dyn. 226(3):446-59.