Publications

Tang X-H, Gudas LJ.  2011.  Retinoids, retinoic acid receptors, and cancer.. Annu Rev Pathol. 6:345-64.

Tang X-H, Gambardella J, Jankauskas S, Wang X, Santulli G, Gudas LJ, Levi R.  2021.  A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.. J Pharmacol Exp Ther. 379(2):182-190.

Tang X-H, Scognamiglio T, Gudas LJ.  2013.  Basal stem cells contribute to squamous cell carcinomas in the oral cavity.. Carcinogenesis. 34(5):1158-64.

Tang X-H, Knudsen B, Bemis D, Tickoo S, Gudas LJ.  2004.  Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.. Clin Cancer Res. 10(1 Pt 1):301-13.

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Tavares TS, Nanus D, Yang XJ, Gudas LJ.  2008.  Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment.. Cancer Biol Ther. 7(10):1607-18.

Thompson JR, Gudas LJ.  2002.  Retinoic acid induces parietal endoderm but not primitive endoderm and visceral endoderm differentiation in F9 teratocarcinoma stem cells with a targeted deletion of the Rex-1 (Zfp-42) gene.. Mol Cell Endocrinol. 195(1-2):119-33.

Tighe AP, Gudas LJ.  2004.  Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells.. J Cell Physiol. 198(2):223-9.

Touma SEllen, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM.  2005.  Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.. Clin Cancer Res. 11(9):3558-66.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2015.  Obesity Leads to Tissue, but not Serum Vitamin A Deficiency.. Sci Rep. 5:15893.

Trasino SE, Gudas LJ.  2015.  Vitamin A: a missing link in diabetes? Diabetes Manag (Lond). 5(5):359-367.

Trasino SE, Benoit YD, Gudas LJ.  2015.  Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.. J Biol Chem. 290(3):1456-73.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2016.  A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.. J Mol Med (Berl). 94(10):1143-1151.

Trasino SE, Tang X-H, Shevchuk MM, Choi ME, Gudas LJ.  2018.  Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor 2 Agonist.. J Pharmacol Exp Ther. 367(1):82-94.

Urvalek AM, Osei-Sarfo K, Tang X-H, Zhang T, Scognamiglio T, Gudas LJ.  2015.  Identification of Ethanol and 4-Nitroquinoline-1-Oxide Induced Epigenetic and Oxidative Stress Markers During Oral Cavity Carcinogenesis.. Alcohol Clin Exp Res. 39(8):1360-72.

Urvalek A, Laursen KBruun, Gudas LJ.  2014.  The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes.. Subcell Biochem. 70:129-49.

Urvalek AM, Gudas LJ.  2014.  Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.. J Biol Chem. 289(28):19519-30.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol.

van der Mijn JC, Laursen KB, Fu L, Khani F, Dow LE, Nowak DG, Chen Q, Gross SS, Nanus DM, Gudas LJ.  2023.  Novel genetically engineered mouse models for clear cell renal cell carcinoma.. Sci Rep. 13(1):8246.

van der Mijn JC, Awamlh BAl Hussein, Khan AIslam, Posada-Calderon L, Oromendia C, Fainberg J, Alshak M, Elahjji R, Pierce H, Taylor B et al..  2019.  Validation of risk factors for recurrence of renal cell carcinoma: Results from a large single-institution series.. PLoS One. 14(12):e0226285.

van der Mijn JC, Chen Q, Laursen KB, Khani F, Wang X, Dorsaint P, Sboner A, Gross SS, Nanus DM, Gudas LJ.  2022.  Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR).. Mol Carcinog.

Wang G, Badylak SF, Heber-Katz E, Braunhut SJ, Gudas LJ.  2010.  The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.. Regen Med. 5(2):201-20.

Wang R, Wang G, Ricard MJ, Ferris B, Strulovici-Barel Y, Salit J, Hackett NR, Gudas LJ, Crystal RG.  2010.  Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.. Chest. 138(6):1402-10.