Publications

Melis M, Trasino SE, Tang X-H, Rappa A, Zhang T, Qin L, Gudas LJ.  2023.  Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease.. Int J Mol Sci. 24(15)

Melis M, Tang X-H, Trasino SE, Gudas LJ.  2022.  Retinoids in the Pathogenesis and Treatment of Liver Diseases.. Nutrients. 14(7)

Melis M, Tang X-H, Trasino SE, Patel VM, Stummer DJ, Jessurun J, Gudas LJ.  2019.  Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.. PLoS One. 14(1):e0211071.

Melis M, Tang X-H, Attarwala N, Chen Q, Prishker C, Qin L, Gross SS, Gudas LJ, Trasino SE.  2021.  A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.. Biofactors.

Melis M, Tang X-H, Mai K, Gudas LJ, Trasino SE.  2022.  Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse.. Pharmacology. :1-11.

Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD et al..  2023.  The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.. Front Cell Dev Biol. 11:1116424.

Minton DR, Fu L, Mongan NP, Shevchuk MM, Nanus DM, Gudas LJ.  2016.  Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma.. Clin Cancer Res. 22(11):2791-801.

Minton DR, Fu L, Chen Q, Robinson BD, Gross SS, Nanus DM, Gudas LJ.  2015.  Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma.. PLoS One. 10(4):e0120649.

Mohn D, Chen SW, Dias DCampos, Weinstein DC, Dyer MA, Sahr K, Ducker CE, Zahradka E, Keller G, Zaret KS et al..  2003.  Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos.. Dev Dyn. 226(3):446-59.

Molina AM, van der Mijn JC, Christos P, Wright J, Thomas C, Dutcher JP, Nanus DM, Tagawa ST, Gudas LJ.  2020.  NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.. Invest New Drugs.

Mongan NP, Gudas LJ.  2005.  Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.. Mol Cancer Ther. 4(3):477-86.

Mongan NP, Martin KM, Gudas LJ.  2006.  The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures.. Mol Carcinog. 45(12):887-900.

Mongan NP, Gudas LJ.  2007.  Diverse actions of retinoid receptors in cancer prevention and treatment.. Differentiation. 75(9):853-70.

Nanus DM, Gudas LJ.  2016.  The Tale of Two Hypoxia-Inducible Factors in Renal Cell Carcinoma.. Eur Urol. 69(4):658-659.

Nilsson EM, Laursen KB, Whitchurch J, McWilliam A, Ødum N, Persson JL, Heery DM, Gudas LJ, Mongan NP.  2015.  MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.. Oncotarget. 6(34):35710-25.

Orfali N, McKenna SL, Cahill MR, Gudas LJ, Mongan NP.  2014.  Retinoid receptor signaling and autophagy in acute promyelocytic leukemia.. Exp Cell Res. 324(1):1-12.

Orfali N, Jeyapalan JN, Woodcock CL, O'Donovan TR, Benjamin D, Cahill M, McKenna S, Gudas LJ, Mongan NP.  2019.  Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.. Methods Mol Biol. 2019:33-49.

Orfali N, O'Donovan TR, Cahill MR, Benjamin D, Nanus DM, McKenna SL, Gudas LJ, Mongan NP.  2020.  All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).. Eur J Haematol. 104(3):236-250.

Orfali N, O'Donovan TR, Nyhan MJ, Britschgi A, Tschan MP, Cahill MR, Mongan NP, Gudas LJ, McKenna SL.  2015.  Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.. Exp Hematol. 43(9):781-93.e2.

Orfali N, Shan-Krauer D, O'Donovan TR, Mongan NP, Gudas LJ, Cahill MR, Tschan MP, McKenna SL.  2019.  Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.. Mol Oncol.

Osei-Sarfo K, Urvalek AM, Tang X-H, Scognamiglio T, Gudas LJ.  2015.  Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model.. Oncotarget. 6(8):6040-52.

Osei-Sarfo K, Gudas LJ.  2014.  Retinoic acid suppresses the canonical Wnt signaling pathway in embryonic stem cells and activates the noncanonical Wnt signaling pathway.. Stem Cells. 32(8):2061-71.

Osei-Sarfo K, Tang X-H, Urvalek AM, Scognamiglio T, Gudas LJ.  2013.  The molecular features of tongue epithelium treated with the carcinogen 4-nitroquinoline-1-oxide and alcohol as a model for HNSCC.. Carcinogenesis. 34(11):2673-81.

Osei-Sarfo K, Gudas LJ.  2019.  Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells.. PLoS One. 14(4):e0215234.

Pérez RJ, Benoit YD, Gudas LJ.  2013.  Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.. Exp Cell Res. 319(14):2196-204.