Publications

Tang X-H, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.  2021.  A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.. J Biol Chem. 297(6):101331.

Melis M, Tang X-H, Attarwala N, Chen Q, Prishker C, Qin L, Gross SS, Gudas LJ, Trasino SE.  2021.  A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.. Biofactors.

Orfali N, O'Donovan TR, Cahill MR, Benjamin D, Nanus DM, McKenna SL, Gudas LJ, Mongan NP.  2020.  All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).. Eur J Haematol. 104(3):236-250.

van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM.  2020.  Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.. Transl Oncol. 13(2):177-185.

Kalish JM, Tang X-H, Scognamiglio T, Zhang T, Gudas LJ.  2020.  Doxycycline-induced exogenous Bmi-1 expression enhances tumor formation in a murine model of oral squamous cell carcinoma.. Cancer Biol Ther. :1-12.

Serio RN, Gudas LJ.  2020.  Modification of stem cell states by alcohol and acetaldehyde.. Chem Biol Interact. 316:108919.

Marta M, Zhang T, Scognamiglio T, Gudas LJ.  2020.  Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma.. Carcinogenesis.

Trasino SE, Tang X-H, Trujillo C, Andres J, Ehrt S, Gudas LJ.  2020.  Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase.. Biochim Biophys Acta Mol Basis Dis. 1866(11):165909.

Molina AM, van der Mijn JC, Christos P, Wright J, Thomas C, Dutcher JP, Nanus DM, Tagawa ST, Gudas LJ.  2020.  NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.. Invest New Drugs.

Serio RN, Lu C, Gross SS, Gudas LJ.  2019.  Different Effects of Knockouts in ALDH2 and ACSS2 on Embryonic Stem Cell Differentiation.. Alcohol Clin Exp Res. 43(9):1859-1871.

Melis M, Tang X-H, Trasino SE, Patel VM, Stummer DJ, Jessurun J, Gudas LJ.  2019.  Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.. PLoS One. 14(1):e0211071.

Serio RN, Laursen KB, Urvalek AM, Gross SS, Gudas LJ.  2019.  Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ.. J Biol Chem. 294(14):5536-5548.

Orfali N, Shan-Krauer D, O'Donovan TR, Mongan NP, Gudas LJ, Cahill MR, Tschan MP, McKenna SL.  2019.  Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.. Mol Oncol.

Orfali N, Jeyapalan JN, Woodcock CL, O'Donovan TR, Benjamin D, Cahill M, McKenna S, Gudas LJ, Mongan NP.  2019.  Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy.. Methods Mol Biol. 2019:33-49.

Osei-Sarfo K, Gudas LJ.  2019.  Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells.. PLoS One. 14(4):e0215234.

van der Mijn JC, Awamlh BAl Hussein, Khan AIslam, Posada-Calderon L, Oromendia C, Fainberg J, Alshak M, Elahjji R, Pierce H, Taylor B et al..  2019.  Validation of risk factors for recurrence of renal cell carcinoma: Results from a large single-institution series.. PLoS One. 14(12):e0226285.

Trasino SE, Tang X-H, Shevchuk MM, Choi ME, Gudas LJ.  2018.  Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor 2 Agonist.. J Pharmacol Exp Ther. 367(1):82-94.

Quintero CM, Laursen KB, Mongan NP, Luo M, Gudas LJ.  2018.  CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.. J Mol Biol. 430(21):4168-4182.

Laursen KB, Gudas LJ.  2018.  Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.. J Biol Chem. 293(30):11891-11900.

Lee M, Gudas LJ, Saavedra HI.  2018.  Detection of E2F-DNA Complexes Using Chromatin Immunoprecipitation Assays.. Methods Mol Biol. 1726:143-151.

Marino A, Sakamoto T, Tang X-H, Gudas LJ, Levi R.  2018.  A Retinoic Acid -Receptor Agonist Exerts Cardioprotective Effects.. J Pharmacol Exp Ther. 366(2):314-321.

Simandi Z, Horvath A, Wright LC, Cuaranta-Monroy I, De Luca I, Karolyi K, Sauer S, Deleuze J-F, Gudas LJ, Cowley SM et al..  2016.  OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation.. Mol Cell. 63(4):647-661.

Trasino SE, Tang X-H, Jessurun J, Gudas LJ.  2016.  A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.. J Mol Med (Berl). 94(10):1143-1151.

Minton DR, Fu L, Mongan NP, Shevchuk MM, Nanus DM, Gudas LJ.  2016.  Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma.. Clin Cancer Res. 22(11):2791-801.

Nanus DM, Gudas LJ.  2016.  The Tale of Two Hypoxia-Inducible Factors in Renal Cell Carcinoma.. Eur Urol. 69(4):658-659.