Publications

DiKun KM, Tang X-H, Fu L, Choi ME, Lu C, Gudas LJ.  2024.  Retinoic acid receptor α activity in proximal tubules prevents kidney injury and fibrosis.. Proc Natl Acad Sci U S A. 121(7):e2311803121.

DiKun KM, Gudas LJ.  2023.  Vitamin A and retinoid signaling in the kidneys.. Pharmacol Ther. 248:108481.

Fernandez CC, Gudas LJ.  2009.  The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells.. J Cell Biochem. 106(3):427-43.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2013.  Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.. Cancer Res. 73(9):2916-25.

Fu L, Minton DR, Zhang T, Nanus DM, Gudas LJ.  2015.  Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome.. Mol Cancer Res. 13(5):870-8.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.  2011.  Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.. Cancer Res. 71(21):6848-56.

Gillespie RF, Gudas LJ.  2007.  Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements.. J Biol Chem. 282(46):33421-34.

Gillespie RF, Gudas LJ.  2007.  Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells.. J Mol Biol. 372(2):298-316.

Goldberg JS, Vargas M, Rosmarin AS, Milowsky MI, Papanicoloau N, Gudas LJ, Shelton G, Feit K, Petrylak D, Nanus DM.  2002.  Phase I trial of interferon alpha2b and liposome-encapsulated all-trans retinoic acid in the treatment of patients with advanced renal cell carcinoma.. Cancer. 95(6):1220-7.

Gudas LJ.  2013.  Retinoids induce stem cell differentiation via epigenetic changes.. Semin Cell Dev Biol. 24(10-12):701-5.

Gudas LJ.  2022.  Retinoid metabolism: new insights.. J Mol Endocrinol.

Gudas LJ.  2012.  Emerging roles for retinoids in regeneration and differentiation in normal and disease states.. Biochim Biophys Acta. 1821(1):213-21.

Gudas R, Rimkūnas A, Staškūnas M.  2021.  Large-Diameter Anterior Cruciate Ligament Reconstruction Technique With 8-Strand Semitendinosus and Gracilis Graft.. Arthrosc Tech. 10(4):e981-e986.

Gudas LJ.  2006.  Stem cells, differentiation and cancer: mentors, colleagues and academic administration.. Cancer Biol Ther. 5(9):1244-6.

Gudas LJ.  2022.  Synthetic Retinoids Beyond Cancer Therapy.. Annu Rev Pharmacol Toxicol. 62:155-175.

Gudas LJ, Wagner JA.  2011.  Retinoids regulate stem cell differentiation.. J Cell Physiol. 226(2):322-30.

Gudas LJ, Fu L, Minton DR, Mongan NP, Nanus DM.  2014.  The role of HIF1α in renal cell carcinoma tumorigenesis.. J Mol Med (Berl). 92(8):825-36.

Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A et al..  2022.  The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.. Cancers (Basel). 14(20)

Harris AE, Lothion-Roy J, Thompson RL, Haque M, Woodcock CL, Alsaleem MA, Dean A, Kariri Y, Toss MS, Gudas LJ et al..  2025.  Functional and clinical significance of the RNA m6A methyltransferase complex in breast cancer.. NPJ Breast Cancer. 11(1):147.

Harris AE, Metzler VM, Lothion-Roy J, Varun D, Woodcock CL, Haigh DB, Endeley C, Haque M, Toss MS, Alsaleem M et al..  2022.  Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.. Front Endocrinol (Lausanne). 13:1006101.

Hedblom A, Laursen KB, Miftakhova R, Sarwar M, Anagnostaki L, Bredberg A, Mongan NP, Gudas LJ, Persson JL.  2013.  CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.. Cell Cycle. 12(8):1251-66.

Hoxie HR, Tang X-H, Gudas LJ.  2025.  Multiple modes of transcriptional regulation by the nuclear hormone receptor RARγ in human squamous cell carcinoma.. J Biol Chem. 302(1):110965.

Huang D, Chen SW, Gudas LJ.  2002.  Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice.. Dev Dyn. 223(3):353-70.

Jeyapalan JN, Metzler VM, de Brot S, Woodcock CL, Harris AE, Lothion-Roy J, Nilsson EM, Ntekim A, Toss MS, Persson JL et al..  2026.  KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer.. Mol Oncol.

Kalish JM, Tang X-H, Scognamiglio T, Zhang T, Gudas LJ.  2020.  Doxycycline-induced exogenous Bmi-1 expression enhances tumor formation in a murine model of oral squamous cell carcinoma.. Cancer Biol Ther. :1-12.